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| | Isophysalin A Basic information |
| Product Name: | Isophysalin A | | Synonyms: | Isophysalin A;PubChem ID: 57387832;1,17:2,6-Dimethano-8H-naphtho[1,2-f]furo[3,4-b:2,3-c']bisoxocin-4,8,11,19(1H,8aH)-tetrone, 2,3,6,6a,9,10,10a,10b,12,16,16a,17-dodecahydro-8a,16,17-trihydroxy-2,6a,10b-trimethyl-3-methylene-, (1S,2S,6R,6aS,8aR,10aS,10bR,16R,16aS,17R,18aS)- | | CAS: | 1363398-67-7 | | MF: | C28H30O10 | | MW: | 526.54 | | EINECS: | | | Product Categories: | | | Mol File: | 1363398-67-7.mol |  |
| | Isophysalin A Chemical Properties |
| Boiling point | 846.6±65.0 °C(Predicted) | | density | 1.55±0.1 g/cm3(Predicted) | | pka | 9.83±0.70(Predicted) |
| | Isophysalin A Usage And Synthesis |
| Uses | Isophysalin A is a physalin with alpha and beta unsaturated ketone components. Isophysalin A binds to GSH and targets multiple cysteine residues on IKKβ. Isophysalin A also inhibits inducible NO synthase (iNOS) and nitric oxide (NO) production, showing anti-inflammatory activity[1]. | | References | [1] Ji L, et al. Physalins with anti-inflammatory activity are present in Physalis alkekengi var. franchetii and can function as Michael reaction acceptors. Steroids. 2012 Apr;77(5):441-7. DOI:10.1016/j.steroids.2011.11.016 |
| | Isophysalin A Preparation Products And Raw materials |
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