- m-Toluoyl chloride
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- $32.00 / 5mg
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2025-07-09
- CAS:1711-06-4
- Min. Order:
- Purity: ≥95%
- Supply Ability: 10g
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| | 3-Methylbenzoyl chloride Basic information |
| | 3-Methylbenzoyl chloride Chemical Properties |
| | 3-Methylbenzoyl chloride Usage And Synthesis |
| Chemical Properties | clear colorless to light brown liquid | | Uses | m-Toluoyl chloride has been used to derivatize the C1-C4 aliphatic amines for their determination in air by HPLC. It has been used in determination of atmospheric ammonia by denuder-sampling and HPLC-UV detection. | | General Description | m-Toluoyl chloride is an efficient derivatization reagent for amines. | | Synthesis | In a 1000 mL three-necked flask equipped with a thermometer, a mechanical stirrer, a reflux condenser tube and an off-gas absorption device, 540.56 g of m-methylbenzoic acid, 573.0 g of thionyl chloride and 1.0 g of N,N-dimethylformamide were added sequentially. The reaction mixture was heated to 90°C and the reaction was continuously stirred at this temperature for 3 hours. Upon completion of the reaction, the system was clear. The excess thionyl chloride was removed by distillation under reduced pressure, and 610.0 g of m-toluoyl chloride was finally obtained, which was determined to have a purity of 98.2% and a yield of 99.3%. | | References | [1] Patent: CN107417518, 2017, A. Location in patent: Paragraph 0028
[2] Patent: CN105348085, 2016, A. Location in patent: Paragraph 0026; 0027; 0028; 0029; 0030
[3] Patent: CN107400052, 2017, A. Location in patent: Paragraph 0016
[4] Canadian Journal of Chemistry, 1963, vol. 41, p. 2962 - 2968
[5] Chemische Berichte, 1879, vol. 12, p. 2300 |
| | 3-Methylbenzoyl chloride Preparation Products And Raw materials |
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