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| | 2-Bromomethyl-1,3-dioxolane Basic information |
| Product Name: | 2-Bromomethyl-1,3-dioxolane | | Synonyms: | 2-(BROMOMETHYL)-1,3-DIOXOLANE/BROMOACETALDEHYDE ETHYLENE ACETAL;2-Brommethyl-,1,3-dioxolane;2-BroMoMethyl-1,3-dioxolane, 97% 25ML;2-Bromomethyl-1,3-dioxolane, 97 %;2-(Bromomethyl)-1,3-dioxolane 98+%;Bromoacetaldehyde ethylene acetal, (1,3-Dioxolan-2-yl)methyl bromide;2-Bromomethyl-1,3-dioxolane 96%;2-(bromomethyl)-3-dioxolane | | CAS: | 4360-63-8 | | MF: | C4H7BrO2 | | MW: | 167 | | EINECS: | 224-443-6 | | Product Categories: | Dioxanes & Dioxolanes;Dioxolanes;Halogenated Heterocycles;Acetals/Ketals/Ortho Esters;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Miscellaneous | | Mol File: | 4360-63-8.mol |  |
| | 2-Bromomethyl-1,3-dioxolane Chemical Properties |
| Boiling point | 80-82 °C27 mm Hg(lit.) | | density | 1.613 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.482(lit.) | | Fp | 145 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Chloroform, Ethyl Acetate (Slightly) | | form | Liquid | | color | Clear colorless | | Water Solubility | Immiscible with water. | | Sensitive | Moisture Sensitive | | BRN | 103309 | | InChI | 1S/C4H7BrO2/c5-3-4-6-1-2-7-4/h4H,1-3H2 | | InChIKey | CKIIJIDEWWXQEA-UHFFFAOYSA-N | | SMILES | BrCC1OCCO1 | | CAS DataBase Reference | 4360-63-8(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Bromomethyl-1,3-dioxolane(4360-63-8) | | EPA Substance Registry System | 1,3-Dioxolane, 2-(bromomethyl)- (4360-63-8) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-24/25 | | WGK Germany | 3 | | TSCA | TSCA listed | | HS Code | 29049090 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2 |
| | 2-Bromomethyl-1,3-dioxolane Usage And Synthesis |
| Chemical Properties | clear colorless liquid | | Uses | 2-Bromomethyl-1,3-dioxolane is used in the preparation of alfa, beta-unsaturated aldehyde and 1, 4-two aldehyde monoacetals synthesis of monomers. | | Uses | 2-Bromomethyl-1,3-dioxolane was used in the synthesis of 1,4-benzoxazepine (BZO) compounds. | | Synthesis | 10.326 kg (166.3 mol) of ethylene glycol and 3.66 kg (83.185 mol) of freshly distilled acetaldehyde were added to the reaction vessel with slow stirring at room temperature for 30 minutes. Slowly 14.622 kg (91.504 mol) of bromine was added dropwise, with the rate of dropwise acceleration being controlled to maintain the reaction temperature at 0-3 °C. After the dropwise addition was completed, the reaction was continued at 0-3 °C for 3.5 hours. Upon completion of the reaction, decompression distillation was carried out to collect the fraction at 80-82 °C/3.6 kPa to give 11.002 kg (65.883 mol) of 2-bromomethyl-1,3-dioxolane in 79.2% yield, which was analyzed to be greater than 95%. | | References | [1] Patent: CN105418612, 2016, A. Location in patent: Paragraph 0028; 0039; 0040 |
| | 2-Bromomethyl-1,3-dioxolane Preparation Products And Raw materials |
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