| Company Name: |
Alinda Chemical Ltd.
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| Tel: |
+7 (495) 672-17-08 |
| Email: |
sale@alinda.ru |
| Products Intro: |
CAS:312281-74-6
Package:1mg Remarks:C19H20Cl2N2O
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| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:BPDBA
CAS:312281-74-6
Purity:97% Package:5mg Remarks:S89931
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| | N-(1-benzylpiperidin-4-yl)-2,4-dichlorobenzamide Basic information |
| | N-(1-benzylpiperidin-4-yl)-2,4-dichlorobenzamide Chemical Properties |
| form | Solid | | color | White to off-white |
| | N-(1-benzylpiperidin-4-yl)-2,4-dichlorobenzamide Usage And Synthesis |
| Description | BPDBA is a noncompetitive inhibitor of the betaine/GABA transporter 1 (BGT1). | | Uses | BPDBA is a selective and noncompetitive betaine/GABA transporter (BGT-1) inhibitor with IC50s of 20 μM and 35 μM against human BGT-1 and mouse GAT2, respectively[1]. | | in vivo | BPDBA is predicted to have excellent oral absorption and blood brain barrier penetration properties[1]. | | References | [1] Kragholm B, et al. Discovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile. Biochem Pharmacol. 2013 Aug 15;86(4):521-8. DOI:10.1016/j.bcp.2013.06.007 |
| | N-(1-benzylpiperidin-4-yl)-2,4-dichlorobenzamide Preparation Products And Raw materials |
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