Algestone acetophenide

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CAS:24356-94-3
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Products Intro: Product Name:Algestone acetophenide
CAS:24356-94-3
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Algestone acetophenide manufacturers

Algestone acetophenide Basic information
Product Name:Algestone acetophenide
Synonyms:16,17-((1-phenylethylidene)bis(oxy))pregn-4-ene-3,20-dione;16-alpha,17-alpha-dihydroxyprogesteroneacetophenide;16-alpha,17-dihydroxypregn-4-ene-3,20-dionecyclicacetalwithacetophenone;17-((1-phenylethylidene)bis(oxy))-20-dion(16-alpha(r))-pregn-4-ene-16;20-dione,16-alpha,17-dihydroxy-pregn-4-ene-cyclicacetalwithacetophenone;3,5-DIETHYL-1,2 DIHYDRO-1-PHENYL-2-PROPYLPYRIDINE (PDHP);alphasoneacetophenide;bovitrol
CAS:24356-94-3
MF:C29H36O4
MW:448.6
EINECS:246-195-8
Product Categories:
Mol File:24356-94-3.mol
Algestone acetophenide Structure
Algestone acetophenide Chemical Properties
Melting point 150-151°
alpha D23 +51° (CHCl3)
Boiling point 477.29°C (rough estimate)
density 1.0455 (rough estimate)
refractive index 1.4800 (estimate)
storage temp. Refrigerator
solubility Chloroform (Sparingly), Methanol (Slightly)
form Solid
color White to Off-White
CAS DataBase Reference24356-94-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Algestone acetophenide Usage And Synthesis
OriginatorNeolutin Depo, Medici ,Italy ,1982
UsesProgestin.
UsesAlgestone Acetophenide is a progestational steroid that has been shown to increase the proteins in milk and serum in goats and decrease the weight gain of kids. Algestone Acetophenide is used as an injectable steroid contraceptive in Chile and Mexico.
DefinitionChEBI: Algestone acetophenide is a 16alpha,17alpha-dihydroxyprogesterone acetophenide. It has a role as an anti-inflammatory drug and a synthetic oral contraceptive.
Manufacturing ProcessTo a suspension of 500 mg of 16α,17α-dihydroxyprogesterone in 25 ml of freshly redistilled acetophenone is added 0.125 ml of 72% perchloric acid and the mixture is agitated at room temperature for one hour. The clear solution is washed with dilute sodium bicarbonate to remove excess acid and the acetophenone layer, after addition of chloroform is separated from the aqueous phase. The organic layer is dried over sodium sulfate and after removal of the chloroform and acetophenone in high vacuum the residue is crystallized from 95% alcohol. The pure acetophenone derivative has a melting point of about 142°C to 144°C.
Brand nameDeladroxone (Bristol-Myers Squibb); Droxone (Bristol-Myers Squibb).
Therapeutic FunctionProgestin, Contraceptive
Algestone acetophenide Preparation Products And Raw materials
Raw materialsAcetophenone
Tag:Algestone acetophenide(24356-94-3) Related Product Information
4-Nitroacetophenone 2-Bromoacetophenone 2'-Hydroxyacetophenone Medroxyprogesterone Acetate Premarin 4'-Methylacetophenone 4'-Hydroxyacetophenone Progesterone 3-Nitroacetophenone Algestone Chalcone Acetophenone ACETALDEHYDE DI-N-HEXYL ACETAL CIS-1,2-CYCLOPENTANEDIOL Alphasone acetonide (S)-Glyceraldehyde acetonide 2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde DIPENTOXYETHANE

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