2',7'-二氟荧光素 基本信息
| 中文名称 | 2',7'-二氟荧光素 |
|---|---|
| 中文同义词 | 2',7'-二氟荧光素;2',7'-二氟-3',6'-二羟基-3H-螺[异苯并呋喃-1,9'-氧杂蒽]-3-酮 |
| 英文名称 | 2',7'-DIFLUOROFLUORESCEIN |
| 英文同义词 | OREGON GREEN(TM) 488;2',7'-Difluoro-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one;2',7'-Difluoro-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one;Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',7'-difluoro-3',6'-dihydroxy-;2',7'-Difluorofluorescein;2',7'-Difluorofluorescein |
| CAS号 | 195136-58-4 |
| 分子式 | C20H10F2O5 |
| 分子量 | 368.29 |
| EINECS号 | |
| 相关类别 | 荧光探针，标记，颗粒和染色 |
| Mol文件 | Mol File |
| 结构式 |  |
2',7'-二氟荧光素 性质
| 沸点 | 591.7±50.0 °C(Predicted) |
|---|---|
| 密度 | 1.70±0.1 g/cm3(Predicted) |
| 溶解度 | 不溶于水；溶于N,N-二甲基甲酰胺 |
| 形态 | 固体 |
| 酸度系数(pKa) | 4.8, (at 22℃);4.7, (at 22℃) |
| 颜色 | 橙色粉末 |
| 外观 | Solid Powder |
| 最大波长(λmax) | 490 nm (Buffer pH 9.0) |
| 主要应用 | 作为地热示踪剂;用于光能转换的TiO2纳米粒子 |
| 生物领域应用 | Detecting atherosclerosis;detecting/monitoring amyloid Aβ production/accumulation/aggregation/disaggregation; diagnosing Alzheimer’s disease;estimating/measuring concentration of cortisol, melatonin, secretory IgA in body fluids;11 evaluating cetuximab-based imaging probe to target epidermal growth factor receptor (EGFR);examining biodistribution of proteins;investigating/measuring protein-protein and protein-nucleic acid interactions;measuring pH of apoplast at the root surface;visualizing hair follicles;as a substrate for measuring β-lactamase activity,phosphatases activity |
| InChI | InChI=1S/C20H10F2O5/c21-13-5-11-17(7-15(13)23)26-18-8-16(24)14(22)6-12(18)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,23-24H |
| InChIKey | FJXJIUHGLVUXQP-UHFFFAOYSA-N |
| SMILES | C12(C3=C(C=C(O)C(F)=C3)OC3=C1C=C(F)C(O)=C3)C1=C(C=CC=C1)C(=O)O2 |