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| | 2-methyl-1-(2,3,4,5,6-pentadeuteriophenyl)propan-2-amine:hydrochloride Basic information |
| | 2-methyl-1-(2,3,4,5,6-pentadeuteriophenyl)propan-2-amine:hydrochloride Chemical Properties |
| solubility | Methanol (Slightly) | | form | Solid | | color | White to Off-White |
| | 2-methyl-1-(2,3,4,5,6-pentadeuteriophenyl)propan-2-amine:hydrochloride Usage And Synthesis |
| Description | Phentermine-d5 (CRM) is intended for use as an internal standard for the quantification of phentermine by GC- or LC-mass spectrometry. Phentermine is an α-methylated amphetamine that activates trace amine associated receptor 1 (TAAR1, EC50 = 5.47 μM). It potently stimulates the release of norepinephrine (IC50 = 39.4 nM), with less effect on the release of dopamine and serotonin (IC50s = 262 and 3,511 nM, respectively). Primarily through these actions, phentermine suppresses appetite and augments fat metabolism, supporting usefulness in ameliorating obesity. | | Uses | Labelled Phentermine (P318830). An Amphetamine derivative.Controlled substance (stimulant). Anorexic. | | References | [1] SEAN MANNING Nicholas F Andrea Pucci. Pharmacotherapy for obesity: novel agents and paradigms.[J]. Therapeutic Advances in Chronic Disease, 2014, 5 3: 135-148. DOI: 10.1177/2040622314522848 [2] NADIA FUCCI Nadia D G. Adulterants encountered in the illicit cocaine market[J]. Forensic science international, 1998, 95 3: Pages 247-252. DOI: 10.1016/s0379-0738(98)00102-9 |
| | 2-methyl-1-(2,3,4,5,6-pentadeuteriophenyl)propan-2-amine:hydrochloride Preparation Products And Raw materials |
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