| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:8-Azidoadenosine-5’-diphosphateSodiumSalt
CAS:102185-14-8
Purity:NULL Package:1mg;2.5mg Remarks:NULL
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| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:8-Azido-ADP disodium
CAS:102185-14-8
Package:50mg/RMB 13800;100mg/RMB 17500;25mg/RMB 10600
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8-AZIDOADENOSINE-5'-O-DIPHOSPHATE SODIUM SALT manufacturers
- 8-Azido-ADP disodium
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- $1980.00 / 50mg
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2025-05-02
- CAS:102185-14-8
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 8-AZIDOADENOSINE-5'-O-DIPHOSPHATE SODIUM SALT Basic information |
| Product Name: | 8-AZIDOADENOSINE-5'-O-DIPHOSPHATE SODIUM SALT | | Synonyms: | 8-azidoadenosine-5’-o-diphosphate(8-n3-adp),sodiumsalt;8-N3-ADP SODIUM SALT;8-Azidoadenosine-5'-diphosphate Sodium Salt;8-Azidoadenosine-5’-diphosphateSodiumSalt;8-Azido-ADP disodium;8-Azidoadenosine-5'-O-diphosphate sodium salt;8-Azidoadenosine-5′-diphosphate Sodium Salt, CAS 102185-14-8 | | CAS: | 102185-14-8 | | MF: | C10H13N8NaO10P2 | | MW: | 490.2 | | EINECS: | | | Product Categories: | | | Mol File: | 102185-14-8.mol |  |
| | 8-AZIDOADENOSINE-5'-O-DIPHOSPHATE SODIUM SALT Chemical Properties |
| solubility | Water: Soluble |
| | 8-AZIDOADENOSINE-5'-O-DIPHOSPHATE SODIUM SALT Usage And Synthesis |
| Uses | 8-Azido-ADP (disodium) is a covalent-binding inhibitor of mitochondrial adenine nucleotide translocation. 8-Azido-ADP (disodium) causes irreversible inhibition of adenine nucleotide exchange in a light-dependent reaction. 8-Azido-ADP (disodium) inhibits the normal state 4 → 3 transitions of mitochondrial respiration induced by ADP[1]. 8-Azido-ADP (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | References | [1] SchHafer G, et al. 8-azido-ADP, a covalent-binding inhibitor of mitochondrial adenine nucleotide translocation. FEBS Lett. 1976 Apr 15;64(1):185-9. DOI:10.1016/0014-5793(76)80279-7
[2] J N DHOLAKIA. Photoaffinity labeling of the rabbit reticulocyte guanine nucleotide exchange factor and eukaryotic initiation factor 2 with 8-azidopurine nucleotides. Identification of GTP- and ATP-binding domains.[J]. The Journal of Biological Chemistry, 1989, 264 34: 20638-20642.
[3] S W CHO H Y Y. Photoaffinity labeling of brain glutamate dehydrogenase isoproteins with an azido-ADP.[J]. The Journal of Biological Chemistry, 1999, 274 20: 13948-13953. DOI: 10.1074/jbc.274.20.13948 |
| | 8-AZIDOADENOSINE-5'-O-DIPHOSPHATE SODIUM SALT Preparation Products And Raw materials |
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