10-(4-methylphenyl)-7-phenyl-6,7,8,10-tetrahydro-5H-indeno[1,2-b]quinoline-9,11-dione

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10-(4-methylphenyl)-7-phenyl-6,7,8,10-tetrahydro-5H-indeno[1,2-b]quinoline-9,11-dione Basic information
Product Name:10-(4-methylphenyl)-7-phenyl-6,7,8,10-tetrahydro-5H-indeno[1,2-b]quinoline-9,11-dione
Synonyms:10-(4-methylphenyl)-7-phenyl-6,7,8,10-tetrahydro-5H-indeno[1,2-b]quinoline-9,11-dione;5H-Indeno[1,2-b]quinoline-9,11-dione, 6,7,8,10-tetrahydro-10-(4-methylphenyl)-7-phenyl-;SARS-CoV-2-IN-100
CAS:374543-46-1
MF:C29H23NO2
MW:417.5
EINECS:
Product Categories:
Mol File:374543-46-1.mol
10-(4-methylphenyl)-7-phenyl-6,7,8,10-tetrahydro-5H-indeno[1,2-b]quinoline-9,11-dione Structure
10-(4-methylphenyl)-7-phenyl-6,7,8,10-tetrahydro-5H-indeno[1,2-b]quinoline-9,11-dione Chemical Properties
Boiling point 645.8±55.0 °C(Predicted)
density 1.30±0.1 g/cm3(Predicted)
pka-1.15±0.60(Predicted)
Safety Information
MSDS Information
10-(4-methylphenyl)-7-phenyl-6,7,8,10-tetrahydro-5H-indeno[1,2-b]quinoline-9,11-dione Usage And Synthesis
UsesSARS-CoV-2-IN-100 (Compound 172) is an inhibitor of SARS-CoV-2, demonstrating broad-spectrum antiviral activity against various SARS-CoV-2 variants. SARS-CoV-2-IN-100 exhibits synergistic effects with Nirmatrelvir, which can reduce the risk of antiviral drug resistance[1].
References[1] Chan C C Y, et al. Identification of novel small-molecule inhibitors of SARS-CoV-2 by chemical genetics[J]. Acta Pharmaceutica Sinica B, 2024. DOI:10.1016/j.apsb.2024.05.026
10-(4-methylphenyl)-7-phenyl-6,7,8,10-tetrahydro-5H-indeno[1,2-b]quinoline-9,11-dione Preparation Products And Raw materials
Tag:10-(4-methylphenyl)-7-phenyl-6,7,8,10-tetrahydro-5H-indeno[1,2-b]quinoline-9,11-dione(374543-46-1) Related Product Information
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