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| | BRD1991 Basic information |
| Product Name: | BRD1991 | | Synonyms: | BRD1991;Benzamide, 3,5-dichloro-N-[[7,8,9,10,11,12-hexahydro-10-(2-hydroxy-1-methylethyl)-8,12-dimethyl-11-oxo-5H-indolo[2,3-h][2,6]benzoxaazacycloundecin-7-yl]methyl]-N-methyl- | | CAS: | 2235468-02-5 | | MF: | C33H35Cl2N3O4 | | MW: | 608.55 | | EINECS: | | | Product Categories: | | | Mol File: | 2235468-02-5.mol |  |
| | BRD1991 Chemical Properties |
| Boiling point | 828.2±65.0 °C(Predicted) | | density | 1.30±0.1 g/cm3(Predicted) | | pka | 14.50±0.10(Predicted) |
| | BRD1991 Usage And Synthesis |
| Description | BRD1991 inhibits Beclin 1/Bcl-2 interaction | | Uses | BRD1991 selectively disrupts Beclin 1/Bcl-2 binding and induces autophagy without triggering apoptosis or other forms of cell death[1]. | | References | [1] Wei-Chung Chiang, et al. High-Throughput Screens To Identify Autophagy Inducers That Function by Disrupting Beclin 1/Bcl-2 Binding. ACS Chem Biol. 2018 Aug 17;13(8):2247-2260. DOI:10.1021/acschembio.8b00421 |
| | BRD1991 Preparation Products And Raw materials |
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