JNJ-28610244 manufacturers
- JNJ-28610244
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- $1520.00
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2026-04-21
- CAS:1251462-28-8
- Purity:
- Supply Ability: 10g
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| | JNJ-28610244 Basic information |
| Product Name: | JNJ-28610244 | | Synonyms: | JNJ-28610244;Methanone, (5-methyl-1H-indol-2-yl)(1-methyl-4-piperidinyl)-, oxime, (1Z)- | | CAS: | 1251462-28-8 | | MF: | C16H21N3O | | MW: | 271.36 | | EINECS: | | | Product Categories: | | | Mol File: | 1251462-28-8.mol |  |
| | JNJ-28610244 Chemical Properties |
| Boiling point | 477.1±45.0 °C(Predicted) | | density | 1.23±0.1 g/cm3(Predicted) | | pka | 12.18±0.48(Predicted) |
| | JNJ-28610244 Usage And Synthesis |
| Description | JNJ-28610244 is a specific H4 receptor agonist that acts by blocking Mac-1-dependent activation of p38 MAPK. | | Uses | JNJ 28610244 is a H4R agonist, with a pKi of 7.3 and pEC50 of 7.0, respectively[1]. | | References | [1] Karim Dib, et al. The histamine H4 receptor is a potent inhibitor of adhesion-dependent degranulation in human neutrophils. J Leukoc Biol. 2014 Sep;96(3):411-8. DOI:10.1189/jlb.2AB0813-432RR |
| | JNJ-28610244 Preparation Products And Raw materials |
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