MPT0B002 manufacturers
- MPT0B002
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- $1520.00
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2026-05-11
- CAS:946077-08-3
- Purity:
- Supply Ability: 10g
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| | MPT0B002 Basic information |
| Product Name: | MPT0B002 | | Synonyms: | MPT0B002;MPT0B002,MPT-0B002;Methanone, (1-methyl-1H-indol-5-yl)(3,4,5-trimethoxyphenyl)- | | CAS: | 946077-08-3 | | MF: | C19H19NO4 | | MW: | 325.36 | | EINECS: | | | Product Categories: | | | Mol File: | 946077-08-3.mol |  |
| | MPT0B002 Chemical Properties |
| Melting point | 119.6-120.8 °C | | Boiling point | 517.0±50.0 °C(Predicted) | | density | 1.17±0.1 g/cm3(Predicted) |
| | MPT0B002 Usage And Synthesis |
| Description | MPT0B002 is a microtubule inhibitor. It acts by downregulating T315I mutant Bcr-Abl and inducing apoptosis of imatinib-resistant chronic myeloid leukemia cell. | | Uses | MPT0B002 is a potent microtubule inhibitor with anticancer activities. MPT0B002 disrupts tubulin polymerization, induces apoptosis, and arrests cell cycle at the G2/M phase[1]. | | References | [1] Yi-Yen Yeh, et al. MPT0B002, a novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells. Invest New Drugs. 2017 Aug;35(4):427-435. DOI:10.1007/s10637-017-0457-9 |
| | MPT0B002 Preparation Products And Raw materials |
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