TH34

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TH34 Suppliers list
Company Name: Shanghai Aladdin Bio-Chem Technology Co.,LTD  
Tel: 400-6206333 13167063860
Email: anhua.mao@aladdin-e.com
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
Tel: 021-52996696，15000506266 15000506266
Email:
Company Name: YouCoChem (Beijing) Chemical Technology Co., Ltd.  
Tel: 18800159827
Email: youcochem@163.com
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Email: huahero21@sina.com
Company Name: BOC Sciences  
Tel: 16314854226
Email: info@bocsci.com

TH34 manufacturers

  • TH34
  • TH34 pictures
  • $38.00
  • 2026-07-14
  • CAS:2196203-96-8
  • Purity: 98.77%
  • Supply Ability: 10g
  • TH34
  • TH34 pictures
  • $9.80
  • 2020-01-09
  • CAS:2196203-96-8
  • Min. Order: 1g
  • Purity: ≥99%
  • Supply Ability: 100kg
TH34 Basic information
Product Name:TH34
Synonyms:TH34;CS-2858;TH34;TH 34;3-(Benzylamino)-N-hydroxy-4-methylbenzamide;TH34,inhibit,Inhibitor,TH 34,TH-34,HDAC,Histone deacetylases;Benzamide, N-hydroxy-4-methyl-3-[(phenylmethyl)amino]-;TH34, 10 mM in DMSO
CAS:2196203-96-8
MF:C15H16N2O2
MW:256.3
EINECS:
Product Categories:
Mol File:2196203-96-8.mol
TH34 Structure
TH34 Chemical Properties
density 1.236±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO : 150 mg/mL (585.25 mM)
pka9.04±0.10(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
TH34 Usage And Synthesis
UsesTH34, an HDAC6/8/10 inhibitor with IC50s of 4.6 μM, 1.9 μM, and 7.7 μM respectively, shows high selectivity over HDAC1/2/3[1].
Biological ActivityTH34 is an HDAC6/8/10 inhibitor with IC50 values of 4.6 μM, 1.9 μM and 7.7 μM, respectively, showing high selectivity compared with HDAC1/2/3.
in vitro

TH34 induces caspase-dependent programmed cell death and cell cycle arrest in neuroblastoma cells.

target

HDAC6

4.6 μM (IC 50 )

HDAC8

1.9 μM (IC 50 )

HDAC10

7.7 μM (IC 50 )

IC 50HDAC6: 4.6 μM (IC50); HDAC8: 1.9 μM (IC50); HDAC10: 7.7 μM (IC50)
References[1] Kolbinger FR, et al. The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines. Arch Toxicol. 2018 Aug;92(8):2649-2664. DOI:10.1007/s00204-018-2234-8
TH34 Preparation Products And Raw materials
Tag:TH34(2196203-96-8) Related Product Information
N-(4-Amino-2-methylphenyl)-3-methylbenzamide 4-amino-N-(2-methylphenyl)benzamide 3,5-dimethyl-N-(2-methylphenyl)benzamide (3-Hydroxycarbamoylphenyl)trimethylammonium iodide TIMTEC-BB SBB000664 N-(3-Amino-2-methylphenyl)-4-methylbenzamide