| Company Name: |
Shanghai Universal Biotech Co.,Ltd
|
| Tel: |
15921930842 15921930842 |
| Email: |
yh-wang@univ-bio.com |
| Products Intro: |
Product Name:Caspase-9 Antibody
Package:100μg Remarks: 见优宁维官网
|
| Company Name: |
Novus Biologicals
|
| Tel: |
400821347 |
| Email: |
orders@novusbio.com |
| Products Intro: |
Product Name:Caspase-9 Antibody
|
| Company Name: |
GeneTex, Inc.
|
| Tel: |
0755-26755892 1-949-553-1900 |
| Email: |
international@genetex.com |
| Products Intro: |
Product Name:Caspase 9 antibody
|
| Company Name: |
NSJ Bioreagents
|
| Tel: |
858.663.9055 8586639055 |
| Email: |
NSJBioname@qq.com |
| Products Intro: |
Product Name:Caspase-9 Antibody
|
|
| | Caspase-9 antibody Chemical Properties |
| | Caspase-9 antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Mouse | | Background | Caspase-9 is an important member of the cysteine aspartic acid protease family. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf-1. Apaf-1 mediated activation of caspase-9 involves intrinsic proteolytic processing, resulting in cleavage at Asp315 and producing a p35 subunit. Another cleavage occurs at Asp330, producing a p37 subunit that can serve to amplify the apoptotic response. Cleaved caspase-9 further processes other caspase members, including caspase-3 and caspase-7, to initiate a caspase cascade, which leads to apoptosis. | | References | [1] Duan, H. et al. (1996) J. Biol. Chem. 271, 16720-16724.
[2] Srinivasula, S. M. et al. (1996) J. Biol. Chem. 271, 27099-27106.
[3] Liu, X. et al. (1996) Cell 86, 147-157.
[4] Li, P. et al. (1997) Cell 91, 479-489.
[5] Zou, H. et al. (1999) J. Biol. Chem. 274, 11549-11556.
[6] Srinivasula, S.M. et al. (1998) Mol Cell 1, 949-57.
[7] Deveraux, Q. L. et al. (1998) EMBO J. 17, 2215-2223.
[8] Slee, E. A. et al. (1999) J. Cell Biol. 144, 281-292.
[9] Sun, X.M. et al. (1999) J Biol Chem 274, 5053-60.
[10] MacFarlane, M. et al. (1997) J. Cell Biol. 137, 469-479. |
| | Caspase-9 antibody Preparation Products And Raw materials |
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