GSK 983)

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GSK 983) Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: Energy Chemical  
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Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
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Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn

GSK 983) manufacturers

  • GSK983
  • GSK983 pictures
  • $1070.00
  • 2026-07-27
  • CAS:827591-02-6
  • Purity:
  • Supply Ability: 10g
GSK 983) Basic information
Product Name:GSK 983)
Synonyms:GSK 983);GSK983 (GSK-983;GSK983 >=98% (HPLC);2-Pyridinecarboxamide, N-[(1R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazol-1-yl]-;2'-chloro-6',7'-dihydrospiro[cyclopropane-1,5'-pyrrolo[2,3-d]pyrimidine]-6'-one
CAS:827591-02-6
MF:C18H16ClN3O
MW:325.79
EINECS:
Product Categories:
Mol File:827591-02-6.mol
GSK 983) Structure
GSK 983) Chemical Properties
Boiling point 627.1±55.0 °C(Predicted)
density 1.38±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 10mg/mL, clear
form Solid
pka13.10±0.20(Predicted)
color White to light yellow
Optical Rotation[α]/D +175 to +195°, c =1 in methylene chloride
InChI1S/C18H16ClN3O/c19-11-7-8-14-13(10-11)12-4-3-6-15(17(12)21-14)22-18(23)16-5-1-2-9-20-16/h1-2,5,7-10,15,21H,3-4,6H2,(H,22,23)
InChIKeyWJQBOBGVBBZLJU-UHFFFAOYSA-N
SMILESClC1=CC=C(NC2=C3CCC[C@H]2NC(C4=NC=CC=C4)=O)C3=C1
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
MSDS Information
GSK 983) Usage And Synthesis
DescriptionGSK983 is a potent broad-spectrum antiviral. It blocks cell proliferation and dengue virus replication by inhibiting the pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase (DHODH).
UsesGSK983 is a broad-spectrum antiviral agent. GSK983 inhibits the replication of adenovirus-5 (Ad-5) and polyoma virus SV40. GSK983 inhibits the growth of cell lines immortalized by EBV, HTLV1, HPV. GSK983 induces the expression of interferon-stimulated genes[1].
References[1] Harvey R,et al. GSK983: a novel compound with broad-spectrum antiviral activity. Antiviral Res. 2009 Apr;82(1):1-11. DOI:10.1016/j.antiviral.2008.12.015
GSK 983) Preparation Products And Raw materials
Tag:GSK 983)(827591-02-6) Related Product Information
9-Acridinecarboxamide, 1,2,3,4-tetrahydro-N-(1-methylethyl)- 1H-Pyrido[3,4-b]indol-1-one, 7-chloro-2,3,4,9-tetrahydro- Benzamide, N-(6-bromo-2,3,4,9-tetrahydro-1H-carbazol-1-yl)-4-methyl- GSK984 >=98% (HPLC) 6-chloro-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one Spiro-[N-benzylpiperidine-4',1-(1,2,3,4-tetrahydro-beta-carboline(4-methylbenzamide))]