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| | 4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE Basic information |
| Product Name: | 4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE | | Synonyms: | 4-[1-HYDROXY-2-[(1-METHYLETHYL)AMINO]BUTYL]-1,2-BENZENEDIOL MESYLATE SALT;4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE;ISOETHARINE MESYLATE;ISOETHARINE MESYLATE SALT;isoetarine mesilate;SOYAGMVKMXZVNZ-UHFFFAOYSA-N;4-[1-hydroxy-2-(propan-2-ylamino)butyl]benzene-1,2-diol,methanesulfonic acid;Adrenergic Receptor,Beta Receptor,Inhibitor,Isoetarine,catechol-like,β-adrenergic Receptors Agonist,emphysema,Isoetharine mesylate salt,inhibit,COMT,bronchodilator,bronchitis,Isoetharine | | CAS: | 7279-75-6 | | MF: | C14H25NO6S | | MW: | 335.42 | | EINECS: | 230-695-8 | | Product Categories: | SYPRINE | | Mol File: | 7279-75-6.mol | ![4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE Structure](CAS/GIF/7279-75-6.gif) |
| | 4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE Chemical Properties |
| storage temp. | 2-8°C | | form | Solid | | color | White to off-white | | InChI | 1S/C13H21NO3.CH4O3S/c1-4-10(14-8(2)3)13(17)9-5-6-11(15)12(16)7-9;1-5(2,3)4/h5-8,10,13-17H,4H2,1-3H3;1H3,(H,2,3,4) | | InChIKey | SOYAGMVKMXZVNZ-UHFFFAOYSA-N | | SMILES | CS(O)(=O)=O.CCC(NC(C)C)C(O)c1ccc(O)c(O)c1 |
| Hazard Codes | Xn | | Risk Statements | 20/21/22 | | Safety Statements | 36 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral |
| | 4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE Usage And Synthesis |
| Uses | Isoetharine Mesylate Salt is a β-adrenergic receptor agonist. Also, it is pregnane X receptor (PXR) activator capable of upregulating CYP450 expression. | | Uses | chelating agent | | Brand name | Bronk ometer (Sanofi Aventis). | | Biological Activity | Isoetharine is an agonist for β-adrenergic receptors and is a bronchodilator. It is a catecholic drug metabolized by sulfotransferases and is present in human urine and plasma as a sulfated metabolite. Catechol O-methyltransferase (COMT) also mediates the methylation of isoetharine in the metabolic conjugation pathway. | | in vivo | Isoetharine mesylate inhibits melanin deposition with the AC50 value of 5.10 mM and complete inhibition of pigment production at 7.50 mM in the zebrafish larvae model[2]. | | IC 50 | β adrenergic receptor |
| | 4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE Preparation Products And Raw materials |
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