6-METHOXYPURINE RIBOSIDE manufacturers
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| | 6-METHOXYPURINE RIBOSIDE Basic information |
| Product Name: | 6-METHOXYPURINE RIBOSIDE | | Synonyms: | 6-METHOXYPURINE RIBOSIDE;6-Methoxypurine ribonucleoside;6-Methoxypurine-9-riboside;9H-Purine, 6-methoxy-9-.beta.-D-ribofuranosyl-;Nsc 30306;Nsc30606;6-Methoxypurine-9-beta-D-riboside;6-O-Methylinosine | | CAS: | 5746-29-2 | | MF: | C11H14N4O5 | | MW: | 282.25 | | EINECS: | | | Product Categories: | | | Mol File: | 5746-29-2.mol |  |
| | 6-METHOXYPURINE RIBOSIDE Chemical Properties |
| Melting point | 140 °C(Solv: methanol (67-56-1); ethyl acetate (141-78-6)) | | Boiling point | 610.7±65.0 °C(Predicted) | | density | 1.84±0.1 g/cm3(Predicted) | | pka | 13.08±0.70(Predicted) |
| | 6-METHOXYPURINE RIBOSIDE Usage And Synthesis |
| Uses | 6-O-Methylinosine is a hypoxanthine analogue. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia[1][2]. | | Definition | ChEBI: 6-O-methylinosine is inosine carrying a methyl substituent on the oxygen at position 6 on the hypoxanthine ring. It has a role as a metabolite. It is functionally related to an inosine. | | References | [1] Virág L, Szabó C. Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death. FASEB J. 2001 Jan;15(1):99-107. DOI:10.1096/fj.00-0299com
[2] Saugstad OD. Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production. Pediatr Res. 1988 Feb;23(2):143-50. DOI:10.1203/00006450-198802000-00001 |
| | 6-METHOXYPURINE RIBOSIDE Preparation Products And Raw materials |
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