| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
18210857532; 18210857532 |
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jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Silybin (Mixture of Silybin A and Silybin B)
CAS:36804-17-8
Purity:98.0%(LC) Package:25G
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| Company Name: |
Meryer (Shanghai) Chemical Technology Co., Ltd.
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| Tel: |
4006356688 18621169109 |
| Email: |
market03@meryer.com |
| Products Intro: |
Product Name:Silybin (Mixture of Silybin A and Silybin B)
CAS:36804-17-8
Purity:>98.0%(LC) Package:25g Remarks:S0508
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| Company Name: |
TCI (Shanghai) Development Co., Ltd.
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| Tel: |
021-67121386 |
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Sales-CN@TCIchemicals.com |
| Products Intro: |
Product Name:Silybin (mixture of Silybin A and Silybin B)
CAS:36804-17-8
Purity:98.0% LC Package:25G,5G
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| | SILYBIN (MIXTURE OF SILYBIN A AND SILYBIN B) Basic information |
| Product Name: | SILYBIN (MIXTURE OF SILYBIN A AND SILYBIN B) | | Synonyms: | Silibinin, 98%(total of isomers);Silibinin
2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxine;(Mixture of Silybin A and Silybin B);Silybin ;SILYBIN (MIXTURE OF SILYBIN A AND SILYBIN B);2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxine;Silybin(mixtureofSilybinAandSilybinB)>;4H-1-Benzopyran-4-one, 2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-rel- | | CAS: | 36804-17-8 | | MF: | C25H22O10 | | MW: | 482.44 | | EINECS: | | | Product Categories: | Biochemistry;Flavonoids | | Mol File: | 36804-17-8.mol |  |
| | SILYBIN (MIXTURE OF SILYBIN A AND SILYBIN B) Chemical Properties |
| Melting point | 160 °C | | Boiling point | 793.0±60.0 °C(Predicted) | | density | 1.527±0.06 g/cm3(Predicted) | | storage temp. | Freezer | | pka | 7.39±0.60(Predicted) | | form | powder to crystaline | | color | White to Orange to Green | | Merck | 14,8532 |
| RTECS | DJ2981770 | | HS Code | 2932.99.7000 |
| | SILYBIN (MIXTURE OF SILYBIN A AND SILYBIN B) Usage And Synthesis |
| Uses | (±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2]. | | Definition | ChEBI: Silibinin is a flavonolignan isolated from milk thistle, Silybum marianum, that has been shown to exhibit antioxidant and antineoplastic activities. It has a role as an antioxidant, an antineoplastic agent, a hepatoprotective agent and a plant metabolite. It is a flavonolignan, a polyphenol, an aromatic ether, a benzodioxine and a secondary alpha-hydroxy ketone. | | References | [1] Silvia Zappavigna, et al. Silybin-Induced Apoptosis Occurs in Parallel to the Increase of Ceramides Synthesis and miRNAs Secretion in Human Hepatocarcinoma Cells. Int J Mol Sci. 2019 May 3;20(9):2190. DOI:10.3390/ijms20092190
[2] Runbin Sun, et al. Silybin ameliorates hepatic lipid accumulation and modulates global metabolism in an NAFLD mouse model. Biomed Pharmacother. 2020 Mar;123:109721. DOI:10.1016/j.biopha.2019.109721 |
| | SILYBIN (MIXTURE OF SILYBIN A AND SILYBIN B) Preparation Products And Raw materials |
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