| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:Doxorubicinol (hydrochloride)
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:Doxorubicinol hydrochloride
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
Cayman Chemical Company
|
| Tel: |
800-364-9897 |
| Email: |
sales@caymanchem.com |
| Products Intro: |
Product Name:Doxorubicinol (hydrochloride)
|
| Company Name: |
Neobioscience Co., Ltd.
|
| Tel: |
4006-800-892 |
| Email: |
info@neobioscience.com |
| Products Intro: |
Product Name:Doxorubicinol (hydrochloride)
|
| Company Name: |
Cayman Chemical Company
|
| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:Doxorubicinol (hydrochloride)
|
|
| | DOXORUBICINOL HYDROCHLORIDE Basic information |
| | DOXORUBICINOL HYDROCHLORIDE Chemical Properties |
| Melting point | >195°C | | solubility | DMSO: Soluble
Methanol: Soluble |
| | DOXORUBICINOL HYDROCHLORIDE Usage And Synthesis |
| Chemical Properties | Dark Red Solid | | Uses | A metabolite of Doxorubicin | | References | [1] S PATEL. Identification of yeast DNA topoisomerase II mutants resistant to the antitumor drug doxorubicin: implications for the mechanisms of doxorubicin action and cytotoxicity.[J]. Molecular Pharmacology, 1997, 52 4: 658-666. DOI: 10.1124/mol.52.4.658
[2] R J BOUCEK. The major metabolite of doxorubicin is a potent inhibitor of membrane-associated ion pumps. A correlative study of cardiac muscle with isolated membrane fractions.[J]. The Journal of Biological Chemistry, 1987, 262 33: 15851-15856.
[3] EMANUELA SALVATORELLI. Paclitaxel and docetaxel stimulation of doxorubicinol formation in the human heart: implications for cardiotoxicity of doxorubicin-taxane chemotherapies.[J]. Journal of Pharmacology and Experimental Therapeutics, 2006, 318 1: 424-433. DOI: 10.1124/jpet.106.103846
[4] ALVARO MORDENTE . Anthracycline secondary alcohol metabolite formation in human or rabbit heart: biochemical aspects and pharmacologic implications[J]. Biochemical pharmacology, 2003, 66 6: Pages 989-998. DOI: 10.1016/s0006-2952(03)00442-8 |
| | DOXORUBICINOL HYDROCHLORIDE Preparation Products And Raw materials |
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