| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester manufacturers
- HCH6-1
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- $58.00
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2026-06-02
- CAS:1435265-06-7
- Purity: 100.00%
- Supply Ability: 10g
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| | D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester Basic information |
| Product Name: | D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester | | Synonyms: | D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester;HCH6-1;Methyl benzoyl-L-tryptophyl-D-phenylalaninate;inhibit,inflammatory,FPR1,HCH6-1,cell infiltration,HCH6 1,antagonist,pulmonary,acute lung injury,lung diseases,ALI,Inhibitor,HCH61,HCH-6-1;Methyl N-benzoyl-L-tryptophyl-D-phenylalaninate;HCH6-1, 10 mM in DMSO | | CAS: | 1435265-06-7 | | MF: | C28H27N3O4 | | MW: | 469.53 | | EINECS: | | | Product Categories: | | | Mol File: | 1435265-06-7.mol |  |
| | D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester Chemical Properties |
| Boiling point | 790.8±60.0 °C(Predicted) | | density | 1.259±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 250 mg/mL (532.45 mM) | | form | Solid | | pka | 13.25±0.46(Predicted) | | color | White to off-white |
| | D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester Usage And Synthesis |
| Uses | HCH6-1 is a selective competitive antagonist of formyl peptide receptor 1 (FPR1) and has protective effects against acute lung injury (ALI). | | in vivo | HCH6-1 (intraperitoneal injection; 50 mg/kg; 1 h before LPS spray or 30 min after LPS spray) alone does not induce airspace inflammation. HCH6-1 pretreatment reduces inflammatory cell infiltration and distortion of pulmonary architecture in the presence of LPS. HCH6-1 posttreatment shows inhibitory effects on neutrophil accumulation and lung damage in LPS-induced ALI mice[1]. | Animal Model: | C57BL/6 mice (20-25 g, 7-8 weeks old)[1] | | Dosage: | 50 mg/kg | | Administration: | Intraperitoneal injection; 50 mg/kg; 1 h before LPS spray or 30 min after LPS spray | | Result: | Ameliorated ALI in LPS-induced mice.HCH6-1-mediated decreasing of neutrophil recruitment serves as a protective mechanism in ALI mice. |
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| | D-Phenylalanine, N-benzoyl-L-tryptophyl-, methyl ester Preparation Products And Raw materials |
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