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| | ERK2 IN-1 Basic information |
| Product Name: | ERK2 IN-1 | | Synonyms: | ERK2 IN-1;ERK2 IN1,ERK2 IN 1,ERK-2 IN-1;3-Pyrrolidinecarboxamide, 1-[2-[3,6-dihydro-4-[4-(2-pyrimidinyl)phenyl]-1(2H)-pyridinyl]-2-oxoethyl]-N-[3-(4-fluorophenyl)-1H-indazol-5-yl]-3-(methylthio)-, (3S)- | | CAS: | 1093061-47-2 | | MF: | C36H34FN7O2S | | MW: | 647.76 | | EINECS: | | | Product Categories: | | | Mol File: | 1093061-47-2.mol |  |
| | ERK2 IN-1 Chemical Properties |
| Boiling point | 858.0±65.0 °C(Predicted) | | density | 1.41±0.1 g/cm3(Predicted) | | pka | 12.89±0.40(Predicted) |
| | ERK2 IN-1 Usage And Synthesis |
| Uses | ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM[1]. | | IC 50 | ERK2: 7 nM (IC50) | | References | [1] Boga SB, Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncology. Bioorg Med Chem Lett. 2018 Jun 15;28(11):2029-2034. DOI:10.1016/j.bmcl.2018.04.063 |
| | ERK2 IN-1 Preparation Products And Raw materials |
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