| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
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| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:AF40431
CAS:181125-92-8
Purity:≥98% Package:100mg 1g,5g,根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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AF40431 manufacturers
- AF40431
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- $242.00
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2026-05-11
- CAS:181125-92-8
- Purity:
- Supply Ability: 10g
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| | AF40431 Basic information |
| Product Name: | AF40431 | | Synonyms: | AF40431;L-Leucine, N-[(7-hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-yl)methyl]-;AF40431,AF-40431 | | CAS: | 181125-92-8 | | MF: | C17H21NO5 | | MW: | 319.35 | | EINECS: | | | Product Categories: | | | Mol File: | 181125-92-8.mol |  |
| | AF40431 Chemical Properties |
| Boiling point | 549.2±50.0 °C(Predicted) | | density | 1.261±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 25 mg/mL (78.28 mM; ultrasonic and adjust pH to 1 with TFA) | | form | Solid | | pka | 2.36±0.21(Predicted) | | color | White to off-white |
| | AF40431 Usage And Synthesis |
| Uses | AF40431, the first reported small-molecule ligand of sortilin, has an IC50 of 4.4 μM and a Kd of 0.7 μM . AF40431 is bound in the neurotensin-binding site of sortilin[1]. | | References | [1] Andersen JL, et al. Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex. Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):451-60. DOI:10.1107/S1399004713030149 |
| | AF40431 Preparation Products And Raw materials |
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