Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]-

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Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]- Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:JTK-101；JTK-1011
CAS:503048-34-8
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:JTK-101
CAS:503048-34-8
Package:25mg;1670USD|100mg;2800USD|50mg;2180USD
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:JTK-101
CAS:503048-34-8
Package:25mg/RMB 11700;100mg/RMB 19500;50mg/RMB 15300

Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]- manufacturers

  • JTK-101
  • JTK-101 pictures
  • $1670.00 / 25mg
  • 2026-04-21
  • CAS:503048-34-8
  • Min. Order:
  • Purity:
  • Supply Ability: 10g
Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]- Basic information
Product Name:Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]-
Synonyms:Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]-;JTK-101;JTK-1011;JTK 101,JTK101
CAS:503048-34-8
MF:C25H23N3O3
MW:413.47
EINECS:
Product Categories:
Mol File:503048-34-8.mol
Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]- Structure
Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]- Chemical Properties
Boiling point 694.576±55.00 °C(Press: 760.00 Torr)(predicted)
density 1.341±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka13.544±0.20(predicted)
Safety Information
MSDS Information
Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]- Usage And Synthesis
UsesJTK-101 is a selective HIV inhibitor. JTK-101 selectively reduces HIV-1 mRNA synthesis by inhibiting Tat cofactors, including CDK9 and cyclin T1, thereby suppressing the transcriptional activity of HIV-1. JTK-101 may be used in the field of anti-HIV virus research[1].
IC 50HIV-1; CDK9/cyclinT1
References[1] Wang X, et al. Potent and selective inhibition of Tat-dependent HIV-1 replication in chronically infected cells by a novel naphthalene derivative JTK-101. Antivir Chem Chemother. 2007;18(4):201-11. DOI:10.1177/095632020701800404
Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]- Preparation Products And Raw materials
Tag:Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]-(503048-34-8) Related Product Information