| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:JTK-101
CAS:503048-34-8
Package:25mg/RMB 11700;100mg/RMB 19500;50mg/RMB 15300
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Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]- manufacturers
- JTK-101
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- $1670.00 / 25mg
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2026-01-05
- CAS:503048-34-8
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]- Basic information |
| Product Name: | Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]- | | Synonyms: | Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]-;JTK-101;JTK-1011;JTK 101,JTK101 | | CAS: | 503048-34-8 | | MF: | C25H23N3O3 | | MW: | 413.47 | | EINECS: | | | Product Categories: | | | Mol File: | 503048-34-8.mol | ![Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]- Structure](CAS/20200515/GIF/503048-34-8.gif) |
| | Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]- Chemical Properties |
| Boiling point | 694.576±55.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.341±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 13.544±0.20(predicted) |
| | Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]- Usage And Synthesis |
| Uses | JTK-101 is a selective HIV inhibitor. JTK-101 selectively reduces HIV-1 mRNA synthesis by inhibiting Tat cofactors, including CDK9 and cyclin T1, thereby suppressing the transcriptional activity of HIV-1. JTK-101 may be used in the field of anti-HIV virus research[1]. | | IC 50 | HIV-1; CDK9/cyclinT1 | | References | [1] Wang X, et al. Potent and selective inhibition of Tat-dependent HIV-1 replication in chronically infected cells by a novel naphthalene derivative JTK-101. Antivir Chem Chemother. 2007;18(4):201-11. DOI:10.1177/095632020701800404 |
| | Benzonitrile, 4-[(3,4-dihydro-9-methoxy-4-oxospiro[2H-naphth[2,1-e]-1,3-oxazine-2,4'-piperidin]-1'-yl)methyl]- Preparation Products And Raw materials |
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