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| | Acetyl Hexapeptide-3 (acetate) Basic information |
| | Acetyl Hexapeptide-3 (acetate) Chemical Properties |
| solubility | PBS (pH 7.2): 10 mg/ml | | Sequence | N-acetyl-Glu-Glu-Met-Gln-Arg-Arg-NH2 |
| | Acetyl Hexapeptide-3 (acetate) Usage And Synthesis |
| Uses | Argireline acetate (Acetyl hexapeptide-3 acetate) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline acetate significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline acetate has antiwrinkle and anti-aging activity[1][2][3]. | | in vivo | Argireline is applied to the aged mice twice daily for 6 weeks. There is an improvement in the histological structure of skin tissue in the aged mice; the amount of type I collagen fibers increased, while that of type III collagen fibers decreased. Argireline could improve the histological structure of skin tissue and rejuvenate the aging skin[3]. | | References | [1] Blanes-Mira C, et al. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002 Oct;24(5):303-10. DOI:10.1046/j.1467-2494.2002.00153.x
[2] Grosicki M, et al. The study of cellular cytotoxicity of argireline - an anti-aging peptide. Acta Biochim Pol. 2014;61(1):29-32. PMID:24644551
[3] Wang Y, et al. The anti-wrinkle efficacy of Argireline. J Cosmet Laser Ther. 2013 Aug;15(4):237-41. DOI:10.3109/14764172.2013.769273 |
| | Acetyl Hexapeptide-3 (acetate) Preparation Products And Raw materials |
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