| Company Name: |
ACROBiosystems |
| Tel: |
13121935750 |
| Email: |
jiaxin.zhao@acrobiosystems.com |
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| Product Name: | BMP4 Protein | | Synonyms: | BMP4 Protein | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![BMP4 Protein Structure]() |
| | BMP4 Protein Chemical Properties |
| | BMP4 Protein Usage And Synthesis |
| Specificity | Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions (PubMed:23407391). | | Reactivity | Human; Mouse; Rat | | Conjugations | Unconjugated | | Clonality | Polyclonal | | Immunogen | Recombinant human Claudin-1 protein (24-161AA) | | Host | Rabbit | | Usage | The predicted MW is 22kDa, while the observed MW by Western blot was 20kDa. | | Format | Biotin, Unmodified | | Specificity | Human CLDN1 / Claudin 1 | | Conjugations | Biotin | | Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human CLDN1 (NP_066924.1). MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV | | Reactivity | Human | | Format | Unconjugated, Unmodified | | Description | Claudin 1 antibody is an unconjugated rabbit polyclonal antibody to human Claudin 1 (CLDN1). Validated for ELISA, IF and IHC. | | Description | Claudin 1 antibody is a biotin-conjugated rabbit polyclonal antibody to human Claudin 1 (CLDN1). Validated for ELISA. | | Description | Claudin 1 antibody is an unconjugated rabbit polyclonal antibody to Claudin 1 (CLDN1) from human. It is reactive with human, mouse and rat. Validated for IHC and WB. | | Application | IHC; IF; ELISA | | Application | ELISA | | Application | IHC; WB | | Target | CLDN1 |
| | BMP4 Protein Preparation Products And Raw materials |
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