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| Product Name: | MOUSE IL-4 | | Synonyms: | IL-4, MOUSE;IL-4 MURINE;INTERLEUKIN-4, MOUSE;INTERLEUKIN-4, MOUSE, RECOMBINANT;INTERLEUKIN-4, MURINE;Recombinant Mouse Interleukin-4;Interleukin-4 from mouse;RECOMBINANT MOUSE IL-4 | | CAS: | 102619-80-7 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | cytokine | | Mol File: | Mol File | ![MOUSE IL-4 Structure]() |
| | MOUSE IL-4 Chemical Properties |
| storage temp. | -20°C | | form | lyophilized powder | | biological source | mouse |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | HS Code | 3504009000 | | Storage Class | 11 - Combustible Solids |
| | MOUSE IL-4 Usage And Synthesis |
| Uses | Interleukin-4 from mouse has been used:
- as a component of cell culture media for class switch recombination assay
- to study its therapeutic benefits for mucosal healing
- as a pioglitazone or new peroxisome proliferator-activated receptor agonist (GQ-11)
| | Biochem/physiol Actions | Interleukin-4 (IL-4) is a lymphokine with profound effects on the growth and differentiation of immunologically competent cells. IL-4 is also known as B cell stimulatory factor-1 (BSF-1), T cell growth factor-2 (TCGF-2) and mast-cell growth factor-2 (MCGF-2). Inhibits VEGF-induced and FGF-Basic-induced angiogenesis. IL-4 is a complex glycoprotein released by a subset of activated T cells. Treatment of IL-4 with specific glycosidases yields an active polypeptide. Human and mouse IL-4 share 50% amino acid sequence homology, but their biological actions are species-specific. | | Description | Interleukin-4 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 120 amino acids and having a molecular mass of 13500 Dalton.
The IL-4 is purified by proprietary chromatographic techniques. | | Source | Escherichia Coli | | Background | Interleukin-4 is a pleiotropic cytokine produced primarily by activated T lymphocytes, basophils and mast cells. Multiple immune response-modulating functions are performed by IL-4 on a variety of cell types and it has an important role in the regulator of isotype switching, induction of IgE production in B lymphocytes and differentiation of precursor T helper cells. IL-4 binds to both membrane-bound and secreted soluble IL-4 receptors. |
| | MOUSE IL-4 Preparation Products And Raw materials |
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