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shlmai |
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021-67680335 13052188602 |
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sale1@shlmai.net |
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| | ANTI-HORMONE SENSITIVE LIPASE Basic information |
| Product Name: | ANTI-HORMONE SENSITIVE LIPASE | | Synonyms: | Anti-LIPE (281-295) antibody produced in rabbit;Anti-LIPE (921-935) antibody produced in rabbit;Anti-HSL antibody produced in rabbit;ANTI-HORMONE SENSITIVE LIPASE;ANTI-HSL;Anti-LHS;Anti-Lipase, hormone-sensitive;LIPE | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-HORMONE SENSITIVE LIPASE Structure]() |
| | ANTI-HORMONE SENSITIVE LIPASE Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| WGK Germany | nwg | | Storage Class | 10 - Combustible liquids |
| | ANTI-HORMONE SENSITIVE LIPASE Usage And Synthesis |
| Uses | Human hormone-sensitive lipase (HSL) gene, containing 9 exons and spanning ~11kB, is mapped to chromosome 19q13.3. HSL is majorly expressed in adipose and steroidogenic tissues, but expressed at low levels in heart and skeletal muscle, macrophages, and islets. Functional HSL exists as a homodimer with high hydrolytic activity. HSL is characterized with a C-terminal catalytic domain, regulatory module and an N-terminal domain responsible for protein–protein and protein–lipid interactions. | | Biological Activity | Hormone-sensitive lipase (HSL) is the major source of energy for most of the tissues. It plays a vital role in hydrolysis of triacylglycerol stored in adipose tissue and possibly steroidogenesis. HSL activity is regulated through reversible phosphorylation by catecholamines and insulin. HSL, also hydrolyzes cholesterol esters in the adrenals, ovaries, testes, and macrophages and plays an essential role in spermatogenesis. HSL mRNA expressed in islets might be implicated in glucose-induced insulin secretion. Abnormality in the protein expression results in obesity, atherosclerosis and type II diabetes. |
| | ANTI-HORMONE SENSITIVE LIPASE Preparation Products And Raw materials |
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