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2-(4-Aminophenyl)ethylamine

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2-(4-Aminophenyl)ethylamine manufacturers

2-(4-Aminophenyl)ethylamine Basic information
Product Name:2-(4-Aminophenyl)ethylamine
Synonyms:4-(2-AMINOETHYL)ANILINE PURUM 97%;p-(2-Aminoethyl)aniline;2-(4-Aminophenyl)ethylamine,95%;1-Amino-2-(4-aminophenyl)ethane 4-(2-Aminoethyl)aniline 4-Aminophenethylamine;4-(2-Aminoethyl)anil;4-Aminophenethylamine, 2-(4-Aminophenyl)ethylamine;4-(2-AMinoethyl)aniline 97%;Aminophenethylamine
CAS:13472-00-9
MF:C8H12N2
MW:136.19
EINECS:236-739-2
Product Categories:Anilines, Aromatic Amines and Nitro Compounds;1
Mol File:13472-00-9.mol
2-(4-Aminophenyl)ethylamine Structure
2-(4-Aminophenyl)ethylamine Chemical Properties
Melting point 28-31 °C(lit.)
Boiling point 103 °C0.3 mm Hg(lit.)
density 1.034 g/mL at 25 °C(lit.)
refractive index n20/D 1.591(lit.)
Fp >230 °F
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Chloroform (Slightly), Methanol (Slightly)
form Viscous Liquid
pka10.32±0.10(Predicted)
color Clear light yellow to brown-yellow
Water Solubility Insoluble in water.
Sensitive Air Sensitive
BRN 1099913
Stability:Air Sensitive
InChI1S/C8H12N2/c9-6-5-7-1-3-8(10)4-2-7/h1-4H,5-6,9-10H2
InChIKeyLNPMZQXEPNWCMG-UHFFFAOYSA-N
SMILESNCCc1ccc(N)cc1
CAS DataBase Reference13472-00-9(CAS DataBase Reference)
NIST Chemistry Reference2-(4-Aminophenyl)ethylamine(13472-00-9)
Safety Information
Hazard Codes C,Xi
Risk Statements 34-20/21/22
Safety Statements 26-36/37/39-45-27
RIDADR UN 3259 8/PG 2
WGK Germany 3
2-10
HazardClass 8
PackingGroup III
HS Code 29215900
Storage Class8A - Combustible corrosive hazardous materials
Hazard ClassificationsSkin Corr. 1B
MSDS Information
ProviderLanguage
2-(4-Aminophenyl)ethylamine English
ACROS English
SigmaAldrich English
2-(4-Aminophenyl)ethylamine Usage And Synthesis
Chemical Propertiesclear light yellow to brown-yellow viscous liquid
Uses4-(2-Aminoethyl)aniline has been used in chemical modification of silk fibroin to tailor the overall hydrophilicity and structure of silk. It has been used as reagent in polycondensation reactions.
Application2-(4-Aminophenyl)ethylamine (APEA) is an important amine compound for the study of reductive amination with 3-deoxy-d-mannuronic acid (Kdo) and for the synthesis of new heat-resistant biopolyureas by fermentation techniques[1-2].
Synthesis Reference(s)Tetrahedron Letters, 25, p. 5219, 1984 DOI: 10.1016/S0040-4039(01)81568-9
General Description4-(2-Aminoethyl)aniline undergoes coupling with carbohydrates by reductive amination to yield modified carbohydrates.
References[1] H D GRIMMECKE; H B. Studies on the reductive amination of 3-deoxy-D-manno-octulosonic acid (Kdo).[J]. Glycoconjugate Journal, 1998. DOI:10.1023/a:1006955508077.
[2] HAJIME MINAKAWA. Fermentative production of 2-(4-aminophenyl)ethylamine to synthesize a novel heat-resistant biopolyurea.[J]. Bioscience, Biotechnology, and Biochemistry, 2022. DOI:10.1093/bbb/zbac077.
2-(4-Aminophenyl)ethylamine Preparation Products And Raw materials
Raw materials4-Nitro-phenethylamine
Preparation ProductsAcetamide,N-[2-(4-aminophenyl)ethyl]-
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