4-Aminoquinoline-2-one manufacturers
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| | 4-Aminoquinoline-2-one Basic information |
| Product Name: | 4-Aminoquinoline-2-one | | Synonyms: | Zinc02550723;4-Amino-2(1H)-quinolinone;4-Aminoquinolin-2(1H)-one;AURORA KA-3886;2(1H)-Quinolinone, 4-amino-;4-amino-1H-quinolin-2-one;4-Aminoquinoline-2-one | | CAS: | 110216-87-0 | | MF: | C9H8N2O | | MW: | 160.17 | | EINECS: | | | Product Categories: | | | Mol File: | 110216-87-0.mol |  |
| | 4-Aminoquinoline-2-one Chemical Properties |
| Melting point | 315℃ | | Boiling point | 393℃ | | density | 1.254 | | Fp | 191℃ | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | 11.27±0.70(Predicted) |
| | 4-Aminoquinoline-2-one Usage And Synthesis |
| Synthesis | Using 4-amino-2-oxo-1,2-dihydroquinoline-3-carboxylic acid (CAS: 833461-40-8, 0.030 g, 0.15 mmol) as the raw material, the reaction was heated at 295 °C for 10 min. After completion of the reaction, the mixture was cooled to room temperature to afford 4-aminoquinolin-2(1H)-one (0.023 g, 99% yield), the product was light yellow solid. Melting point: >250 °C. 1H NMR (400 MHz, DMSO-d6) δ 5.42 (s, 1H), 6.55 (s, 2H), 7.07 (t, J = 7.6 Hz, 1H), 7.19 (d, J = 8.0 Hz, 1H), 7.42 (t, J = 7.2 Hz, 1H), 7.86 (d, J = 7.6 Hz, 1H). 10.71 (s, 1H). Mass spectrometry (MS) showed the molecular ion peak m/z 161 (MH+). | | References | [1] Patent: US2008/306053, 2008, A1. Location in patent: Page/Page column 71
[2] Chemistry of Heterocyclic Compounds, 2006, vol. 42, # 4, p. 475 - 487 |
| | 4-Aminoquinoline-2-one Preparation Products And Raw materials |
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