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Phthalazine

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CAS:253-52-1
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CAS:253-52-1
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CAS:253-52-1
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Phthalazine manufacturers

  • Phthalazine
  • Phthalazine pictures
  • $0.00 / 25kg
  • 2025-05-12
  • CAS:253-52-1
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 5 MTs
  • Phthalazine
  • Phthalazine pictures
  • $1.00 / 1KG
  • 2019-07-06
  • CAS:253-52-1
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: Customized
Phthalazine Basic information
Product Name:Phthalazine
Synonyms:2,3-Diazanaphthalene;beta-Phenodiazine;β-Phenodiazine;4,5-BENZOPYRIDAZINE;2,3-BENZODIAZINE;BENZO[D]PYRIDAZINE;PHTHALAZINE;PHZ
CAS:253-52-1
MF:C8H6N2
MW:130.15
EINECS:205-963-2
Product Categories:Building Blocks;Heterocyclic Building Blocks;Pyridazines
Mol File:253-52-1.mol
Phthalazine Structure
Phthalazine Chemical Properties
Melting point 89-92 °C(lit.)
Boiling point 189 °C29 mm Hg(lit.)
density 1.1509 (rough estimate)
refractive index 1.6231 (estimate)
Fp 178-180°C/15mm
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka3.47(at 20℃)
form Crystalline Powder
color Slightly brown to beige
Water Solubility Soluble in water, methanol, chloroform.
Merck 14,7370
BRN 109240
InChI1S/C8H6N2/c1-2-4-8-6-10-9-5-7(8)3-1/h1-6H
InChIKeyLFSXCDWNBUNEEM-UHFFFAOYSA-N
SMILESc1ccc2cnncc2c1
CAS DataBase Reference253-52-1(CAS DataBase Reference)
NIST Chemistry ReferencePhthalazine(253-52-1)
EPA Substance Registry SystemPhthalazine (253-52-1)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-68
Safety Statements 24/25-37/39-36-26-36/37/39
WGK Germany 3
TSCA TSCA listed
HS Code 29339900
Storage Class11 - Combustible Solids
Hazard ClassificationsAquatic Chronic 3
Muta. 2
MSDS Information
ProviderLanguage
2,3-Benzodiazine English
ACROS English
SigmaAldrich English
ALFA English
Phthalazine Usage And Synthesis
Chemical PropertiesSLIGHTLY BROWN TO BEIGE CRYSTALLINE POWDER
UsesPhthalazine is a heterocyclic organic compound isomeric with quinoxaline, cinnoline and quinazoline. Aminophthalazine compounds serve as effective phosphodiesterase (PDE) inhibitors.
UsesPhthalazine derivatives including copper and platinum complexes were induce the apoptosis in breast cancer cell lines and renal hyperemia.
DefinitionChEBI: Phthalazine is an azaarene that is the 2,3-diaza analogue of naphthalene. The parent of the class of phthalazines. It is a mancude organic heterobicyclic parent, a member of phthalazines, an azaarene and an ortho-fused heteroarene.
Synthesis Reference(s)Journal of Heterocyclic Chemistry, 2, p. 206, 1965 DOI: 10.1002/jhet.5570020219
Purification MethodsPhthalazine crystallises from diethyl ether or *benzene, and sublimes under a vacuum. The hydrochloride forms needles from EtOH with m 235-236o(dec) and the picrate has m 208-210o. [Armarego J Appl Chem 11 70 1961, Beilstein 23 H 174, 23 III/IV 1233.]
Phthalazine Preparation Products And Raw materials
Preparation Products1-CHLOROPHTHALAZINE-->Hyaluronidase-->Cadralazine-->Ophthazin-->2-Ethyl-3-methylnaphthalene
Tag:Phthalazine(253-52-1) Related Product Information
DBU Phthalylsulfathiazole Phthalhydrazide Phthaloyl amlodipine Phthalic anhydride Ophthazin Todralazine hydrochloride (DHQ)2PHAL 1,4-Dichlorophthalazine 1-BENZYL-4-CHLOROPHTHALAZINE 1-CHLOROPHTHALAZINE Dihydralazine sulphate 1-(2-(1,3-DIMETHYL-2-BUTENYLIDENE)HYDRAZINO)PHTHALAZINE METHYL 2-[(4-BENZYL-1-PHTHALAZINYL)SULFANYL]ACETATE Phthalazine 1-BENZYL-4-[(4-CHLOROBENZYL)SULFANYL]PHTHALAZINE 1-BENZYL-4-(4-METHOXYPHENOXY)PHTHALAZINE 4-[(4-BENZYL-1-PHTHALAZINYL)OXY]BENZENECARBONITRILE