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| | [TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN Basic information |
| Product Name: | [TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN | | Synonyms: | TYR-VAL-ASN-TRP-LEU-LEU-ALA-GLN-LYS-GLY-LYS-LYS-ASN-ASP-TRP-LYS-HIS-ASN-ILE-THR-GLN;[Tyr0] Gastric Inhibitory Peptide (23-42), human: [Tyr22] Gastric Inhibitory Peptide (22-42), human;TYR-VAL-ASN-TRP-LEU-LEU-ALA-GLN-LYS-GLY-LYS-LYS-ASN-ASP-TRP-LYS-HIS-ASN-ILE-THR-GLN: YVNWLLAQKGKKNDWKHNITQ;[Tyr22] Gastric Inhibitory Peptide (22-42), human;[TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN | | CAS: | 121765-67-1 | | MF: | C119H182N34O31 | | MW: | 2584.93 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![[TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN Structure](StructureFile/ChemBookStructure2/GIF/CB5754809.gif) |
| | [TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN Chemical Properties |
| | [TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN Usage And Synthesis |
| Uses | [Tyr0] Gastric Inhibitory Peptide (23-42), human, a glucose-dependent insulinotropic polypeptide (GIP), is a weak inhibitor of gastric acid secretion that also stimulates insulin secretion. [Tyr0] Gastric Inhibitory Peptide (23-42), human can be used in diabetes, obesity research[1][2]. | | in vivo | GIPR-/- mice have higher blood glucose levels and impaired initial insulin response after oral glucose loading. In GIPR+/+ mice, a high-fat diet did not increase postprandial intake blood glucose levels, whereas it significantly increased in GIPR-/- mice[2].
| | References | [1] LaPelusa A, et al. Biochemistry, Bombesin[M]//StatPearls [Internet]. StatPearls Publishing, 2021. [2] K Miyawaki, et al. Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14843-7. DOI:10.1073/pnas.96.26.14843 |
| | [TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN Preparation Products And Raw materials |
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