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| | PEG7-O-Ms Basic information |
| Product Name: | PEG7-O-Ms | | Synonyms: | PEG7-O-Ms;2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl methanesulfonate;3,6,9,12,15,18-Hexaoxaeicosane-1,20-diol, 1-methanesulfonate | | CAS: | 1217601-12-1 | | MF: | C15H32O10S | | MW: | 404.47 | | EINECS: | | | Product Categories: | | | Mol File: | 1217601-12-1.mol |  |
| | PEG7-O-Ms Chemical Properties |
| Boiling point | 528.3±50.0 °C(Predicted) | | density | 1.192±0.06 g/cm3(Predicted) | | solubility | Soluble in Water, DMSO, DCM, DMF | | pka | 14.36±0.10(Predicted) |
| | PEG7-O-Ms Usage And Synthesis |
| Description | PEG8-Ms is a PEG linker containing a mesyl group and a hydroxyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media. | | Uses | PEG7-O-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | PEG7-O-Ms Preparation Products And Raw materials |
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