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| | AKOS 92543 Basic information |
| Product Name: | AKOS 92543 | | Synonyms: | AKOS 92543;2-phenyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one;[1]Benzothieno[2,3-d]pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-2-phenyl-;CL-300619;2-Phenyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one;Antiproliferative agent-15 | | CAS: | 19819-18-2 | | MF: | C16H14N2OS | | MW: | 282.36 | | EINECS: | | | Product Categories: | | | Mol File: | 19819-18-2.mol |  |
| | AKOS 92543 Chemical Properties |
| form | Solid | | color | Off-white to light yellow |
| | AKOS 92543 Usage And Synthesis |
| Uses | Antiproliferative agent-15 is an thienopyrimidine derivated anticancer agent. Antiproliferative agent-15 shows antiproliferative activity against human colon (HCT116 and HCT15) and brain (LN-229 and GBM-10) cancer cell lines[1]. | | References | [1] Haneen Amawi, et al. Thienopyrimidine derivatives exert their anticancer efficacy via apoptosis induction, oxidative stress and mitotic catastrophe. Eur J Med Chem. 2017 Sep 29;138:1053-1065. DOI:10.1016/j.ejmech.2017.07.028 |
| | AKOS 92543 Preparation Products And Raw materials |
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