Cyanine 5 NHS Ester manufacturers
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| | Cyanine 5 NHS Ester Basic information |
| Product Name: | Cyanine 5 NHS Ester | | Synonyms: | Cyanine5 NHS ester (tetrafluoroborate);Cyanine5 NHS ester（BF4）;1-(6-((2,5-Dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)-3,3-dimethyl-2-(5-(1,3,3-trimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-3H-indol-1-ium tetrafluoroborate;Cyanine5 NHS ester, Amine-reactive red emitting fluorescent dye.;Cy5-NHS ester tetrafluoroborate;Cy5-M SE (FIR);1-((2R,3R,4R,5R)-3-azido-4-(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione | | CAS: | 1263093-76-0 | | MF: | C36H42BF4N3O4 | | MW: | 667.55 | | EINECS: | | | Product Categories: | | | Mol File: | 1263093-76-0.mol |  |
| | Cyanine 5 NHS Ester Chemical Properties |
| solubility | very poorly soluble in water (0.19 mM = 127 mg/L), good in polar (DMSO, DMF) and chlorinated (DCM, chloroform) organic solvents | | Appearance | dark colored solid | | InChIKey | LWGOCTDPEVJNTC-UHFFFAOYSA-N | | SMILES | [B+3]([F-])([F-])([F-])[F-].C([N+]1=C(C(C)(C)C2=CC=CC=C12)C=CC=CC=C1C(C2=CC=CC=C2N1C)(C)C)CCCCC(=O)ON1C(CCC1=O)=O |
| | Cyanine 5 NHS Ester Usage And Synthesis |
| Description | This Cyanine5 NHS ester, also known as Cy5 NHS ester, is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires a small amount of organic co-solvent to be used in labeling reactions. This reagent is ideal for very cost-efficient labeling of soluble proteins as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. | | Uses | Cyanine 5 NHS ester tetrafluoroborate (Compound Cy5) is a cyanine dye that is used to in fluorescence detection of macromolecules. Cyanine 5 NHS ester tetrafluoroborate exhibits an excitation wavelength of 638 nm[1]. | | References | [1] Kang J, et al., Prevention of H‐aggregates formation in Cy5 labeled macromolecules[J]. International Journal of Polymer Science, 2010, 2010(1): 264781. | | Abs/Em Maxima | 646/662 nm | | Fluoresene quantum yield | 0.2 | | Extinction Coefficient | 250000 | | CF260 | 0.03 | | CF280 | 0.04 |
| | Cyanine 5 NHS Ester Preparation Products And Raw materials |
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