1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-2-deoxy-α-L-threo-pentofuranosyl]-3-[(2-fluoro-4-methylphenyl)thio]-

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1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-2-deoxy-α-L-threo-pentofuranosyl]-3-[(2-fluoro-4-methylphenyl)thio]- Suppliers list
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1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-2-deoxy-α-L-threo-pentofuranosyl]-3-[(2-fluoro-4-methylphenyl)thio]- manufacturers

  • ATG7-IN-1
  • ATG7-IN-1 pictures
  • $329.00
  • 2026-09-10
  • CAS:2226229-87-2
  • Purity: 99.85%
  • Supply Ability: 10g
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-2-deoxy-α-L-threo-pentofuranosyl]-3-[(2-fluoro-4-methylphenyl)thio]- Basic information
Product Name:1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-2-deoxy-α-L-threo-pentofuranosyl]-3-[(2-fluoro-4-methylphenyl)thio]-
Synonyms:1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-2-deoxy-α-L-threo-pentofuranosyl]-3-[(2-fluoro-4-methylphenyl)thio]-;ATG7 IN 1,ATG7IN1,ATG-7-IN-1;ATG7-IN-1
CAS:2226229-87-2
MF:C17H19FN6O5S2
MW:470.49
EINECS:
Product Categories:
Mol File:2226229-87-2.mol
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-2-deoxy-α-L-threo-pentofuranosyl]-3-[(2-fluoro-4-methylphenyl)thio]- Structure
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-2-deoxy-α-L-threo-pentofuranosyl]-3-[(2-fluoro-4-methylphenyl)thio]- Chemical Properties
Boiling point 748.9±70.0 °C(Predicted)
density 1.82±0.1 g/cm3(Predicted)
pka9.15±0.70(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-2-deoxy-α-L-threo-pentofuranosyl]-3-[(2-fluoro-4-methylphenyl)thio]- Usage And Synthesis
UsesATG7-IN-1 is a potent and selective inhibitor of ATG7 (IC50 = 62 nM).
References[1] Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28(19):115681. DOI:10.1016/j.bmc.2020.115681
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-2-deoxy-α-L-threo-pentofuranosyl]-3-[(2-fluoro-4-methylphenyl)thio]- Preparation Products And Raw materials
Tag:1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-2-deoxy-α-L-threo-pentofuranosyl]-3-[(2-fluoro-4-methylphenyl)thio]-(2226229-87-2) Related Product Information
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