- RS 504393
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- $43.00
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2026-05-11
- CAS:300816-15-3
- Purity: 99.68%
- Supply Ability: 10g
- RS 504393
-
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2025-04-04
- CAS:300816-15-3
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1Ton
- RS 504393
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- $5.50
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2020-01-13
- CAS:300816-15-3
- Min. Order: 1IU
- Purity: 98%min
- Supply Ability: 1kg-100kg
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| | RS 504393 Basic information |
| Product Name: | RS 504393 | | Synonyms: | Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 6-Methyl-1'-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethyl]-;6-Methyl-1'-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidi;6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin]-2(;6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin];RS 504393;6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one;RS-504393; RS504393;RS504393 >=98% (HPLC) | | CAS: | 300816-15-3 | | MF: | C25H27N3O3 | | MW: | 417.5 | | EINECS: | | | Product Categories: | | | Mol File: | 300816-15-3.mol |  |
| | RS 504393 Chemical Properties |
| density | 1.28 | | storage temp. | 2-8°C | | solubility | DMSO: soluble1mg/mL, clear (warmed) | | form | powder | | color | white to beige | | InChI | 1S/C25H27N3O3/c1-17-8-9-22-20(16-17)25(31-24(29)27-22)11-14-28(15-12-25)13-10-21-18(2)30-23(26-21)19-6-4-3-5-7-19/h3-9,16H,10-15H2,1-2H3,(H,27,29) | | InChIKey | ODNICNWASXKNNQ-UHFFFAOYSA-N | | SMILES | N3(CCC4(OC(=O)Nc5c4cc(cc5)C)CC3)CCc1nc([o]c1C)c2ccccc2 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | RS 504393 Usage And Synthesis |
| Uses | RS 504393 is a small molecule antagonist at the CC chemokine receptor 2. | | Uses | RS504393 has been used in mass spectrometry. | | Definition | ChEBI: 6-methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-2-spiro[1H-3,1-benzoxazine-4,4'-piperidine]one is a member of 1,3-oxazoles. | | Biological Activity | Extremely selective CCR2 chemokine receptor antagonist (IC 50 values are 98 nM and > 100 μ M for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Inhibits MCP-1 chemotaxis (IC 50 = 330 nM) and ischemia-reperfusion injury in kidneys. | | Biochem/physiol Actions | RS504393 is a highly selective CCR2 chemokine receptor antagonist. RS504393 inhibits MCP-1 chemotaxis and ischemia-reperfusion injury in kidneys. | | storage | Store at +4°C |
| | RS 504393 Preparation Products And Raw materials |
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