1-Propanone, 1-(2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]dec-3-yl)-3-(1H-indol-3-yl)- manufacturers
- AF-710B
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2026-09-15
- CAS:1235733-73-9
- Min. Order: 10g
- Purity: 99%
- Supply Ability: 20ton
- AF-710B
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- $200.00
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2026-08-18
- CAS:1235733-73-9
- Purity: 99.93%
- Supply Ability: 10g
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| | 1-Propanone, 1-(2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]dec-3-yl)-3-(1H-indol-3-yl)- Basic information |
| Product Name: | 1-Propanone, 1-(2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]dec-3-yl)-3-(1H-indol-3-yl)- | | Synonyms: | 1-Propanone, 1-(2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]dec-3-yl)-3-(1H-indol-3-yl)-;1-(2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]decan-3-yl)-3-(1H-indol-3-yl)propan-1-one;(Rac)-AF710B;AF 710B;AF710B;AF-710B;1-(2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]dec-3-yl)-3-(1H-indol-3-yl)-1-propanone | | CAS: | 1235733-73-9 | | MF: | C20H27N3OS | | MW: | 357.51 | | EINECS: | | | Product Categories: | pharmaceutical | | Mol File: | 1235733-73-9.mol | ![1-Propanone, 1-(2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]dec-3-yl)-3-(1H-indol-3-yl)- Structure](CAS/20210305/GIF/1235733-73-9.gif) |
| | 1-Propanone, 1-(2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]dec-3-yl)-3-(1H-indol-3-yl)- Chemical Properties |
| Boiling point | 591.0±50.0 °C(Predicted) | | density | 1.24±0.1 g/cm3(Predicted) | | pka | 17.16±0.30(Predicted) |
| | 1-Propanone, 1-(2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]dec-3-yl)-3-(1H-indol-3-yl)- Usage And Synthesis |
| Uses | (Rac)-AF710B is the racemate of AF710B (HY-116586). AF710B is a highly potent and selective allosteric M1 muscarinic and σ1 receptor agonist. AF710B can be used for the research of Alzheimer’s disease[1]. | | References | [1] Fisher A, et al. AF710B, a Novel M1/σ1 Agonist with Therapeutic Efficacy in Animal Models of Alzheimer’s Disease. Neurodegener Dis. 2016;16(1-2):95-110. DOI:10.1159/000440864 |
| | 1-Propanone, 1-(2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]dec-3-yl)-3-(1H-indol-3-yl)- Preparation Products And Raw materials |
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