Acetamide, 2-chloro-N-[4-(4-methoxyphenoxy)phenyl]-N-(phenylmethyl)-

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Acetamide, 2-chloro-N-[4-(4-methoxyphenoxy)phenyl]-N-(phenylmethyl)- manufacturers

  • CCW16
  • CCW16 pictures
  • $30.00
  • 2026-04-20
  • CAS:2361138-33-0
  • Purity: 97.00%
  • Supply Ability: 10g
Acetamide, 2-chloro-N-[4-(4-methoxyphenoxy)phenyl]-N-(phenylmethyl)- Basic information
Product Name:Acetamide, 2-chloro-N-[4-(4-methoxyphenoxy)phenyl]-N-(phenylmethyl)-
Synonyms:Acetamide, 2-chloro-N-[4-(4-methoxyphenoxy)phenyl]-N-(phenylmethyl)-;CCW16;N-Benzyl-2-chloro-N-(4-(4-methoxyphenoxy)phenyl)acetamide, E3 ubiquitin ligase ligand, Ligand for PROTAC? research, RNF4-targeting ligand;N-benzyl-2-chloro-N-[4-(4-methoxyphenoxy)phenyl]acetamide
CAS:2361138-33-0
MF:C22H20ClNO3
MW:381.85
EINECS:
Product Categories:
Mol File:2361138-33-0.mol
Acetamide, 2-chloro-N-[4-(4-methoxyphenoxy)phenyl]-N-(phenylmethyl)- Structure
Acetamide, 2-chloro-N-[4-(4-methoxyphenoxy)phenyl]-N-(phenylmethyl)- Chemical Properties
Boiling point 533.2±50.0 °C(Predicted)
density 1.240±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka0.86±0.50(Predicted)
form Solid
color Light yellow to yellow
InChI1S/C22H20ClNO3/c1-26-19-11-13-21(14-12-19)27-20-9-7-18(8-10-20)24(22(25)15-23)16-17-5-3-2-4-6-17/h2-14H,15-16H2,1H3
InChIKeyDPADEQNOMBTITM-UHFFFAOYSA-N
SMILESCOC1=CC=C(OC2=CC=C(N(CC3=CC=CC=C3)C(CCl)=O)C=C2)C=C1
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
Hazard ClassificationsAquatic Acute 1
Aquatic Chronic 1
MSDS Information
Acetamide, 2-chloro-N-[4-(4-methoxyphenoxy)phenyl]-N-(phenylmethyl)- Usage And Synthesis
UsesCCW16 is a cofactor for the synthesis of protein degraders, such as PROTACs CCW 28-3 (HY-156774).
reaction suitabilityreagent type: ligand
IC 50RNF4
References[1] Ward CC, et, al. Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. DOI:10.1021/acschembio.8b01083
Acetamide, 2-chloro-N-[4-(4-methoxyphenoxy)phenyl]-N-(phenylmethyl)- Preparation Products And Raw materials
Tag:Acetamide, 2-chloro-N-[4-(4-methoxyphenoxy)phenyl]-N-(phenylmethyl)-(2361138-33-0) Related Product Information
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