- Trimetozine
-
- $29.00 / 5mg
-
2026-01-20
- CAS:635-41-6
- Min. Order:
- Purity: 83.05%
- Supply Ability: 10g
- Trimetozine
-
- $29.00 / 5mg
-
2026-01-20
- CAS:635-41-6
- Min. Order:
- Purity: 83.05%
- Supply Ability: 10g
- Trimetozine
-
- $31.00 / 5mg
-
2025-05-01
- CAS:635-41-6
- Min. Order:
- Purity: 98.81%
- Supply Ability: 10g
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| | trimetozine Basic information |
| | trimetozine Chemical Properties |
| Melting point | 120-122° | | Boiling point | 423.97°C (rough estimate) | | density | 1.1755 (rough estimate) | | refractive index | 1.5230 (estimate) | | pka | -1.60±0.20(Predicted) | | form | Solid | | color | White to off-white |
| Toxicity | LD50 oral in rat: 1800mg/kg |
| | trimetozine Usage And Synthesis |
| Originator | Opalene,Theraplix,France,1966 | | Uses | A sedative with mild tranquilizing effects. Trimetozine has been used therapeutically in the treatment of anxiety. It is also a metabolite of the antisecretory and antiulcer drug Trithiozine. | | Uses | antiurolithic, depigmentation, radiation protectant | | Uses | A sedative with mild tranquilizing effects. It has been used therapeutically in the treatment of anxiety. It is also a metabolite of the antisecretory and antiulcer drug Trithiozine. | | Definition | ChEBI: 4-morpholinyl-(3,4,5-trimethoxyphenyl)methanone is a member of morpholines. | | Manufacturing Process | 46 g 3,4,5-trimethoxybenzoyl chloride are dissolved in 300 ml anhydrous
benzene and 25 g triethylamine and thereafter 19 g anhydrous morpholine are
added in small portions with ice-cooling. The solution is boiled for 2 hours
under reflux. The precipitate is filtered off, and the solution is washed with
dilute sulfuric acid, then with sodium hydrogen carbonate solution and finally
with water, and then evaporated. The residual yellow oil soon crystallizes; the
crystalline mass of the desired material is taken up with ether, filtered and
then recrystallized from 90% ethanol, from which it separates in prisms. It is
slightly soluble in water. Yield: 80%. melting point 120°C to 122°C. | | Therapeutic Function | Sedative |
| | trimetozine Preparation Products And Raw materials |
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