2-Naphthaleneacetic acid, α-ethyl-6-methoxy- manufacturers
- MDK-0738
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- $1520.00
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2026-05-11
- CAS:56600-73-8
- Purity:
- Supply Ability: 10g
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| | 2-Naphthaleneacetic acid, α-ethyl-6-methoxy- Basic information |
| | 2-Naphthaleneacetic acid, α-ethyl-6-methoxy- Chemical Properties |
| Boiling point | 414.5±20.0 °C(Predicted) | | density | 1.170±0.06 g/cm3(Predicted) | | pka | 4.81±0.30(Predicted) |
| | 2-Naphthaleneacetic acid, α-ethyl-6-methoxy- Usage And Synthesis |
| Description | MDK-0738, also known as AKR1C3-IN-14a, is a potent and selective aldo-keto reductase 1C3 inhibitor. The name MDK-0738 uses the last four digits of the CAS registry number for this compound. MDK-0738 displays selectivity for AKR1C3 over other AKR1C enzymes and COX. | | Uses | AKR1C2/3-IN-2 is a potential AKR1C3 inhibitor with selective AKR1C3 activity. AKR1C2/3-IN-2 is able to block AKR1C3-mediated testosterone (T) production and PSA induction, affecting the endocrine activity of prostate cancer cells. AKR1C2/3-IN-2 shows selectivity over other AKR1C enzymes, indicating its potential application in inhibiting drug-resistant prostate cancer. AKR1C2/3-IN-2 has no inhibitory activity against COX isomerases, further emphasizing its specificity as a prostate cancer inhibitory compound[1]. | | References | [1] Discovery of (R)-2-(6-Methoxynaphthalen-2-yl)butanoic Acid as a Potent and Selective Aldo-keto Reductase 1C3 Inhibitor |
| | 2-Naphthaleneacetic acid, α-ethyl-6-methoxy- Preparation Products And Raw materials |
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