|
|
| | 1-hydrazino-3-(methylthio)propan-2-ol Basic information |
| Product Name: | 1-hydrazino-3-(methylthio)propan-2-ol | | Synonyms: | 1-hydrazino-3-(methylthio)propan-2-ol;1-Hydrazino-3-methylthio-2-propanol;2-propanol,1-hydrazinyl-3-(methylthio);Einecs 238-332-5;1-hydrazinyl-3-(Methylthio)-2-Propanol;1-hydrazinyl-3-(methylthio)propan-2-ol;Nifuratel Impurity 9;Nifuratel-4 | | CAS: | 14359-97-8 | | MF: | C4H12N2OS | | MW: | 136.22 | | EINECS: | 238-332-5 | | Product Categories: | | | Mol File: | 14359-97-8.mol |  |
| | 1-hydrazino-3-(methylthio)propan-2-ol Chemical Properties |
| Boiling point | 128-130 °C(Press: 1 Torr) | | density | 1.145±0.06 g/cm3(Predicted) | | pka | 13.98±0.20(Predicted) |
| | 1-hydrazino-3-(methylthio)propan-2-ol Usage And Synthesis |
| Chemical Properties | White powder | | Uses | 1-hydrazino-3-(methylthio)propan-2-ol, also known as 3-methylmercapto-2-hydroxy-propyl hydrazine, is an important organic reagent that can be used as a building block for the synthesis of many organic compounds. It can be used to synthesize N-amino-5-methylmercapto-methyl-2-oxazolidinone which is an intermediate of nifuratel. | | Synthesis | Add 226.25g hydrazine hydrate to 1000ml reaction flask, heat to 90℃, and add 104.17g of glycidyl ether under stirring. The temperature of the reaction system was controlled at 90℃, and then the excess hydrazine hydrate was concentrated under reduced pressure to obtain 120.10g thick colorless liquid. The purity of the gas phase was 96.8%, namely 1-hydrazino-3-(methylthio)propan-2-ol, and the yield was 88.30%.
 |
| | 1-hydrazino-3-(methylthio)propan-2-ol Preparation Products And Raw materials |
|