Phenol, 4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-

Request For Quotation
Phenol, 4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]- Suppliers list
Company Name: Emeishan Hongsen Biopharmaceutical Co., Ltd.  
Tel: 0833-6186278 19162541913
Email: sales@hongshengpharm.com
Company Name: BioPharmaMatrix,Inc.  
Tel: 0510-86010668 13395169561;
Email: sales@biopharmamatrix.com
Company Name: Shanghai SuperLan Chemcial Technique Centre  
Tel: 0-2022843681 15618226720
Email: chaolaichem@foxmail.com
Company Name: Dideu Industries Group Limited  
Tel: +8617392712697
Email: 1022@dideu.com
Company Name: Shanghai UCHEM Inc.  
Tel: +86-18930848214 +86-021-56762820
Email: sales@myuchem.com

Phenol, 4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]- manufacturers
Phenol, 4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]- Basic information
Product Name:Phenol, 4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-
Synonyms:Phenol, 4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-;4-(6-{[4-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)phenol
CAS:2489876-34-6
MF:C17H12F3N3O2
MW:347.29
EINECS:
Product Categories:
Mol File:2489876-34-6.mol
Phenol, 4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]- Structure
Phenol, 4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]- Chemical Properties
Boiling point 481.0±45.0 °C(Predicted)
density 1.411±0.06 g/cm3(Predicted)
pka8.18±0.30(Predicted)
Safety Information
MSDS Information
Phenol, 4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]- Usage And Synthesis
UsesPROTAC BCR-ABL1 ligand 1, compound GMB-475, is the ligand of PROTAC that allosterically targets BCR-ABL1 protein and recruits the E3 ligase Von Hippel-Lindau, resulting in ubiquitination and subsequent degradation of BCR-ABL1[1].
References[1] Burslem GM, et al. Targeting BCR-ABL1 in Chronic Myeloid Leukemia by PROTAC-Mediated Targeted Protein Degradation. Cancer Res. 2019 Sep 15;79(18):4744-4753. DOI:10.1158/0008-5472.CAN-19-1236
Phenol, 4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]- Preparation Products And Raw materials
Tag:Phenol, 4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-(2489876-34-6) Related Product Information
AT9283 Protein Tyrosine Kinase Compound Library Anti-cancer compound library Ibrutinib Ponatinib Asciminib