3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride

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3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride manufacturers
3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride Basic information
Product Name:3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride
Synonyms:3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride;Benzoquinamide hydrochloride;2-Acetoxy-3-diethylcarbamoyl-9,10-dimethoxyhexahydrobenzo(A)quinolizine hydrochloride;2H-Benzo(A)quinolizine-3-carboxamide, N,N-diethyl-1,3,4,6,7,11B-hexahydro-2-hydroxy-9,10-dimethoxy-, acetate (ester), hydrochloride;3-Carbamoyl-N,N-diethyl-1,3,4,6,7,11B-hexahydro-9,11-dimethoxy-2H-benzo(A)quinolizin-2-yl acetate hydrochloride;Benzochinamide hydrochloride;Benzquinamida clorhidrato;Benzquinamida clorhidrato [spanish]
CAS:113-69-9
MF:C22H35ClN2O5
MW:442.9767
EINECS:204-033-3
Product Categories:Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:113-69-9.mol
3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride Structure
3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride Chemical Properties
Melting point 229-231 °C
solubility Acetonitrile: Slightly soluble: 0.1-10 mg/ml
DMSO: Sparingly soluble: 1-10 mg/ml
form Solid
color Off-white to light yellow
Safety Information
ToxicityLD50 orl-rat: 990 mg/kg TXAPA9 18,185,71
MSDS Information
3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride Usage And Synthesis
UsesAntipsychotic; antiemetic.
Safety ProfilePoison by intraperitoneal route.Moderately toxic by ingestion. When heated todecomposition it emits very toxic fumes of Cl - and NOx.A tranquilizer and antiemetic.
References[1] ELISABET GREGORI-PUIGJANÉ. Identifying mechanism-of-action targets for drugs and probes.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2012: 11178-11183. DOI: 10.1073/pnas.1204524109
[2] NIEMEGEERS C J. Antiemetic specificity of dopamine antagonists.[J]. Psychopharmacology, 1982, 78 3: 210-213. DOI: 10.1007/bf00428152
[3] D. SMITH. Cardiovascular Effects of Benzquinamide[J]. Anesthesia & Analgesia, 1979, 4 1: 189-194. DOI: 10.1213/00000539-197905000-00006
3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride Preparation Products And Raw materials
Tag:3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride(113-69-9) Related Product Information
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