T-1840383 manufacturers
- T-1840383
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- $1520.00
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2026-07-27
- CAS:1195779-24-8
- Purity:
- Supply Ability: 10g
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| | T-1840383 Basic information |
| | T-1840383 Chemical Properties |
| | T-1840383 Usage And Synthesis |
| Description | T-1840383 is a novel inhibitor of HGF-induced c-Met phosphorylation and VEGF-induced VEGFR-2 phosphorylation in cancer epithelial cells and vascular endothelial cells. | | Uses | T-1840383 is a potent, ATP-competitive inhibitor of c-Met/VEGFR-2, with the IC50s of 1.9 nM, 7.7 nM, 2.2 nM and 5.5 nM for c-Met, VEGFR1, VEGFR2 and VEGFR3, respectively[1]. | | References | [1] Z Yuan, et al. Advances on receptor tyrosine kinase inhibitors taking c-Met as anti-tumor target. Journal of China Pharmaceutical University. |
| | T-1840383 Preparation Products And Raw materials |
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