4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)-

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4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)- manufacturers

  • MDK-4204
  • MDK-4204 pictures
  • $1980.00
  • 2026-05-11
  • CAS:1983924-20-4
  • Purity:
  • Supply Ability: 10g
4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)- Basic information
Product Name:4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)-
Synonyms:4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)-;Anticancer Agent I;Anticancer AgentI;Anticancer Agent-I;MDK 4204;MDK4204;MDK-4204
CAS:1983924-20-4
MF:C31H29FN4O
MW:492.59
EINECS:
Product Categories:
Mol File:1983924-20-4.mol
4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)- Structure
4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)- Chemical Properties
Boiling point 702.5±70.0 °C(Predicted)
density 1.17±0.1 g/cm3(Predicted)
pka2.91±0.20(Predicted)
Safety Information
MSDS Information
4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)- Usage And Synthesis
UsesAnticancer agent 255 is a monocarbonylated curcumin-1,2,3-oxazole conjugate with significant anticancer activity. The IC50 values of Anticancer agent 255 in prostate cancer cells PC-3 and DU-145 are 8.8μM and 9.5μM respectively. The IC50 values of Anticancer agent 255 against breast cancer cells MCF-7, MDA-MB-231 and 4T1 are 6μM, 10μM and 6.4μM, showing good anti-cancer activity Effect. Anticancer agent 255 can induce mitochondria-mediated apoptosis in cancer cells and prevent cell cycle progression. Anticancer agent 255 down-regulated the cell proliferation marker PCNA and inhibited the activation of cell survival proteins. Anticancer agent 255 up-regulated the pro-apoptotic protein Bax and down-regulated the anti-apoptotic protein Bcl-2[1].
References[1] Synthesis and biological evaluation of some novel triazole hybrids of curcumin mimics and their selective anticancer activity against breast and prostate cancer cell lines
4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)- Preparation Products And Raw materials
Tag:4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)-(1983924-20-4) Related Product Information
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