2-Butenamide, 4-(dimethylamino)-N-[4-[[[2-[[[8-(1-methylethyl)-2-[(1-methyl-4-piperidinyl)oxy]pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]phenyl]amino]methyl]phenyl]-, (2E)-

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2-Butenamide, 4-(dimethylamino)-N-[4-[[[2-[[[8-(1-methylethyl)-2-[(1-methyl-4-piperidinyl)oxy]pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]phenyl]amino]methyl]phenyl]-, (2E)- Suppliers list
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2-Butenamide, 4-(dimethylamino)-N-[4-[[[2-[[[8-(1-methylethyl)-2-[(1-methyl-4-piperidinyl)oxy]pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]phenyl]amino]methyl]phenyl]-, (2E)- Basic information
Product Name:2-Butenamide, 4-(dimethylamino)-N-[4-[[[2-[[[8-(1-methylethyl)-2-[(1-methyl-4-piperidinyl)oxy]pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]phenyl]amino]methyl]phenyl]-, (2E)-
Synonyms:2-Butenamide, 4-(dimethylamino)-N-[4-[[[2-[[[8-(1-methylethyl)-2-[(1-methyl-4-piperidinyl)oxy]pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]phenyl]amino]methyl]phenyl]-, (2E)-;CDK7-IN-5
CAS:1817006-50-0
MF:C34H45N9O2
MW:611.78
EINECS:
Product Categories:
Mol File:1817006-50-0.mol
2-Butenamide, 4-(dimethylamino)-N-[4-[[[2-[[[8-(1-methylethyl)-2-[(1-methyl-4-piperidinyl)oxy]pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]phenyl]amino]methyl]phenyl]-, (2E)- Structure
2-Butenamide, 4-(dimethylamino)-N-[4-[[[2-[[[8-(1-methylethyl)-2-[(1-methyl-4-piperidinyl)oxy]pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]phenyl]amino]methyl]phenyl]-, (2E)- Chemical Properties
density 1.23±0.1 g/cm3(Predicted)
pka13.32±0.70(Predicted)
Safety Information
MSDS Information
2-Butenamide, 4-(dimethylamino)-N-[4-[[[2-[[[8-(1-methylethyl)-2-[(1-methyl-4-piperidinyl)oxy]pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]phenyl]amino]methyl]phenyl]-, (2E)- Usage And Synthesis
UsesCDK7-IN-5 is a CDK7 inhibitor with an IC50 value <100 nM. CDK7-IN-5 has anticancer effects. (WO2015154022A1 (Compound 104))[1].
IC 50CDK7: <100 nM (IC50)
References[1] Jason J. MARINEAU, et al. Inhibitors of cyclin-dependent kinase 7 (cdk7). WO2015154022A1.
2-Butenamide, 4-(dimethylamino)-N-[4-[[[2-[[[8-(1-methylethyl)-2-[(1-methyl-4-piperidinyl)oxy]pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]phenyl]amino]methyl]phenyl]-, (2E)- Preparation Products And Raw materials
Tag:2-Butenamide, 4-(dimethylamino)-N-[4-[[[2-[[[8-(1-methylethyl)-2-[(1-methyl-4-piperidinyl)oxy]pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]phenyl]amino]methyl]phenyl]-, (2E)-(1817006-50-0) Related Product Information
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