Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino- (9CI)

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Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino- (9CI) Basic information
Product Name:Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino- (9CI)
Synonyms:Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino- (9CI);3-Aminobicyclo[1.1.1]pentane-1-carboxylicacid;Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino-;BGT1-IN-1
CAS:406947-32-8
MF:C6H9NO2
MW:127.14
EINECS:
Product Categories:AMINEPRIMARY;AMINOACID;1
Mol File:406947-32-8.mol
Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino- (9CI) Structure
Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino- (9CI) Chemical Properties
Boiling point 252.1±40.0 °C(Predicted)
density 1.607±0.06 g/cm3(Predicted)
pka2.90±0.20(Predicted)
form solid
color White
Safety Information
HS Code 2922498590
MSDS Information
Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino- (9CI) Usage And Synthesis
UsesBGT1-IN-1 (compound 9) is a potent BGT1 inhibitor with IC50 value of 13.9, 58.3 μM for hBGT1, GAT3, respectively. BGT1-IN-1 shows no cytotoxic. BGT1-IN-1 shows neuroprotective activity[1].
References[1] tka K, et al. Rational Search for Betaine/GABA Transporter 1 Inhibitors─In Vitro Evaluation of Selected Hit Compound. ACS Chem Neurosci. 2024 Oct 19. DOI:10.1021/acschemneuro.4c00425
Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino- (9CI) Preparation Products And Raw materials
Tag:Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino- (9CI)(406947-32-8) Related Product Information
Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino-, hydrochloride 3-[(tert-Butoxycarbonyl)amino]bicyclo[1.1.1]pentane-1-carboxylic acid 3-{[(benzyloxy)carbonyl]amino}bicyclo[1.1.1]pentane-1-carboxylic acid Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-aMino-, Methyl ester, hydrochloride (9CI) Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino-, methyl ester (9CI) 3-Aminobicyclo[1.1.1]pentane-1-carbonitrile