Ethanaminium, 2-[[[(2R)-2,3-dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-tri(methyl-d3)-, inner salt

Ethanaminium, 2-[[[(2R)-2,3-dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-tri(methyl-d3)-, inner salt Suppliers list
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CAS:2260669-07-4
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CAS:2260669-07-4
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CAS:2260669-07-4
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CAS:2260669-07-4
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Products Intro: Product Name:[D9]-sn-Glycero-3-Phosphocholine
CAS:2260669-07-4
Package:1mg
Ethanaminium, 2-[[[(2R)-2,3-dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-tri(methyl-d3)-, inner salt Basic information
Product Name:Ethanaminium, 2-[[[(2R)-2,3-dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-tri(methyl-d3)-, inner salt
Synonyms:Ethanaminium, 2-[[[(2R)-2,3-dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-tri(methyl-d3)-, inner salt;(R)-2,3-dihydroxypropyl(2-(tris(methyl-d3)ammonio)ethyl)phosphate;[D9]-sn-Glycero-3-Phosphocholine;sn-Glycero-3-phosphocholine-d9 (GPC-d9)
CAS:2260669-07-4
MF:C8H20NO6P
MW:257.22
EINECS:
Product Categories:
Mol File:2260669-07-4.mol
Ethanaminium, 2-[[[(2R)-2,3-dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-tri(methyl-d3)-, inner salt Structure
Ethanaminium, 2-[[[(2R)-2,3-dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-tri(methyl-d3)-, inner salt Chemical Properties
storage temp. -20°C
solubility Methanol: Slightly Soluble; Water: Slightly Soluble
form A solid
color Colorless to light yellow
Safety Information
WGK Germany WGK 1
Storage Class10 - Combustible liquids
MSDS Information
Ethanaminium, 2-[[[(2R)-2,3-dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-tri(methyl-d3)-, inner salt Usage And Synthesis
Descriptionsn-glycero-3-Phosphocholine-d9 is intended for use as an internal standard for the quantification of sn-glycero-3-phosphocholine by GC- or LC-MS. sn-glycero-3-Phosphocholine is a nootropic phospholipid, a precursor to choline biosynthesis, and an intermediate in the metabolism of phosphatidylcholine.1 In vivo, sn-glycero-3-phosphocholine is converted to phosphorylcholine, a metabolically active form of choline that increases acetylcholine synthesis and release in rat hippocampus. It prevents scopolamine-induced amnesia in a passive avoidance test in rats and exerts neuroprotective effects in models of altered cholinergic neurotransmission and models of brain vascular injury.1,2
Usessn-Glycero-3-phosphocholine-d9 is the deuterium labeled sn-Glycero-3-phosphocholine. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia[1][2].
References1. Traini, E., Bramanti, V., and Amenta, F. Choline alphoscerate (alpha-glyceryl-phosphoryl-choline) an old choline- containing phospholipid with a still interesting profile as cognition enhancing agent. Curr. Alzheimer Res. 10(10),1070-1079(2013).
2. Sigala, S., Imperato, A., Rizzonelli, P., et al. L-α-glycerylphosphorylcholine antagonizes scopolamine-induced amnesia and enhances hippocampal cholinergic transmission in the rat Eur. J. Pharmacol. 211(3),351-358(1992).
Ethanaminium, 2-[[[(2R)-2,3-dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-tri(methyl-d3)-, inner salt Preparation Products And Raw materials
Tag:Ethanaminium, 2-[[[(2R)-2,3-dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-tri(methyl-d3)-, inner salt(2260669-07-4) Related Product Information
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