- 3-Thienylmethylamine
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- $1.10 / 1g
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2025-11-18
- CAS:27757-86-4
- Min. Order: 1g
- Purity: 99.00%
- Supply Ability: 100 Tons
- 3-Thienylmethylamine
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- $8.80 / 1KG
-
2019-07-11
- CAS:27757-86-4
- Min. Order: 1KG
- Purity: 97%-99%
- Supply Ability: 100kg
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| | 3-Thienylmethylamine Basic information |
| Product Name: | 3-Thienylmethylamine | | Synonyms: | RARECHEM AL BW 0778;BUTTPARK 121\50-76;C-THIOPHEN-3-YL-METHYLAMINE;3-(Aminomethyl)thiophene;(3-thienylmethyl)amine(SALTDATA: HCl);Thiophen-3-yl-methylamine;(Thien-3-yl)methylamine;3-ThiopheneMethylaMine | | CAS: | 27757-86-4 | | MF: | C5H7NS | | MW: | 113.18 | | EINECS: | | | Product Categories: | CHIRAL CHEMICALS | | Mol File: | 27757-86-4.mol |  |
| | 3-Thienylmethylamine Chemical Properties |
| Boiling point | 102°C (15 mmHg) | | density | 1.130 | | refractive index | 1.5660 | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 9.57±0.29(Predicted) | | form | clear liquid | | color | Colorless to Light yellow | | Water Solubility | Slightly soluble in water. | | Sensitive | Air Sensitive | | InChI | InChI=1S/C5H7NS/c6-3-5-1-2-7-4-5/h1-2,4H,3,6H2 | | InChIKey | DUDAKCCDHRNMDJ-UHFFFAOYSA-N | | SMILES | C1SC=CC=1CN |
| Hazard Codes | C | | Risk Statements | 34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | 2735 | | Hazard Note | Corrosive | | HazardClass | IRRITANT | | HazardClass | 8 | | PackingGroup | Ⅲ | | HS Code | 29349990 |
| | 3-Thienylmethylamine Usage And Synthesis |
| Chemical Properties | Colorless liquid | | Uses | 3-Thiophenemethylamineis an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. | | Synthesis | General procedure for the synthesis of 3-aminomethylthiophene from 3-cyanothiophene: Ruthenium(II) complex (1 M) and 2-butanol (5 mL) were added to a 25 mL flask under argon protection and stirred for 5 min at room temperature. Subsequently, KOtBu (0.05 mM) was added and stirring was continued for 5 minutes. Next, 3-cyanothiophene (0.5 mM) was added and the reaction mixture was heated on a hot plate at 120°C for 30 minutes. Upon completion of the reaction, the catalyst was removed by addition of petroleum ether followed by filtration. The filtrate was neutralized with 1 M HCl. The ether layer was purified by short path silica gel column chromatography. Hexadecane was added to the purified filtrate as an internal standard and the yield of the product 3-aminomethylthiophene was determined by gas chromatography (GC). | | References | [1] Organic Process Research and Development, 2012, vol. 16, # 1, p. 109 - 116
[2] Chemistry - A European Journal, 2016, vol. 22, # 14, p. 4991 - 5002
[3] Angewandte Chemie - International Edition, 2016, vol. 55, # 47, p. 14653 - 14657
[4] Angew. Chem., 2016, vol. 128, # 47, p. 14873 - 14877,5
[5] Journal of Coordination Chemistry, 2015, vol. 68, # 2, p. 321 - 334 |
| | 3-Thienylmethylamine Preparation Products And Raw materials |
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