Benzenesulfonamide, 3-(4-benzoyl-2-ethyl-2,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)- manufacturers
- TK4g
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- $2500.00
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2026-07-27
- CAS:2232890-86-5
- Purity:
- Supply Ability: 10g
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| | Benzenesulfonamide, 3-(4-benzoyl-2-ethyl-2,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)- Basic information |
| | Benzenesulfonamide, 3-(4-benzoyl-2-ethyl-2,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)- Chemical Properties |
| Boiling point | 580.8±60.0 °C(Predicted) | | density | 1.355±0.06 g/cm3(Predicted) | | pka | 10.02±0.60(Predicted) |
| | Benzenesulfonamide, 3-(4-benzoyl-2-ethyl-2,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)- Usage And Synthesis |
| Uses | TK4g is a Janus kinase (JAK) inhibitor with the IC50 values of 12.61 nM and 15.80 nM for JAK2 and JAK3, respectively. TK4g can be used in lymphoid-derived diseases and leukemia cancer research[1]. | | IC 50 | JAK2: 12.61 nM (IC50); JAK3: 15.80 nM (IC50) | | References | [1] Kamonpan Sanachai, et al. Pharmacophore-Based Virtual Screening and Experimental Validation of Pyrazolone-Derived Inhibitors toward Janus Kinases. ACS Omega 2022. |
| | Benzenesulfonamide, 3-(4-benzoyl-2-ethyl-2,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)- Preparation Products And Raw materials |
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